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[背侧海马去甲肾上腺素在大鼠自我刺激反应机制中的作用]

[Role of noradrenaline of the dorsal hippocampus in the mechanism of self-stimulation reaction in rats].

作者信息

Gasanov G G, Melikov E M, Movsumov G D

出版信息

Biull Eksp Biol Med. 1990 Jan;109(1):5-6.

PMID:2110487
Abstract

In has been established that intrahippocampal bilateral injection of NA did not influence common frequency of lateral hypothalamic self stimulation. After the destruction of hippocampal NA - terminals of 6-OHDA increased the frequency of self stimulation and rearing. It is suggested that NA hippocampus inhibit the recall trace of the memory of sensory reinforcement stimuli in the course of stimulation "reward".

摘要

已经确定,海马体内双侧注射去甲肾上腺素(NA)不会影响下丘脑外侧自我刺激的常见频率。在6-羟基多巴胺破坏海马NA终末后,自我刺激和竖毛频率增加。这表明在“奖励”刺激过程中,海马去甲肾上腺素抑制感觉强化刺激记忆的回忆痕迹。

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