Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510102, China.
Chin J Integr Med. 2010 Dec;16(6):493-7. doi: 10.1007/s11655-010-0563-4. Epub 2010 Nov 26.
To analyze the effectiveness of Chinese medicine and integrated Chinese and Western medicine for influenza A (H1N1) in the fever clinics and its relevant expenditure.
A prospective survey on the clinical epidemic observation and follow-up was conducted from July 2009 to October 2009 with a self-developed questionnaire whose contents including the clinical data of the confirmed 149 H1N1 cases and their relevant therapeutic expenditure. The patients were assigned to the Chinese medicine group (22 cases treated by Chinese medicine alone) and integrative medicine group (124 cases treated by both Chinese medicine and Western medicine). The data were processed with descriptive analysis, t test and χ (2), and sum-rank test.
The proportion of clinical recovery of Chinese medicine group (81.8%) was higher than that of integrative medicine group (54.8%) with statistical significance (P=0.02). The average fever durations in both groups were 3.5 to 4 days, showing no significant difference (P=0.86). In the comparisons of average cost of Chinese herbs, drugs, therapies, and total cost, those of the Chinese medicine group were lower than those in the integrative group (P=0.01, P=0.00, P=0.00, P=0.00).
The H1N1 patients in the fever clinic who received Chinese medicine treatment had a higher clinical recovery proportion than those who received integrated Chinese and Western medicine treatment with lower medical cost. However, due to small sample size of the Chinese medicine group in the study, the conclusion needs further confirmation by studies with large sample size.
分析流感发热门诊中中药及中西医结合治疗甲型 H1N1 流感的疗效及其相关费用。
采用自行设计的临床观察及随访问卷,对 2009 年 7 月至 10 月确诊的 149 例甲型 H1N1 流感患者进行前瞻性调查,内容包括患者的临床资料和相关治疗费用。将患者分为中药组(22 例,单纯中药治疗)和中西医结合组(124 例,中药加西药治疗),采用描述性分析、t 检验、χ²检验和秩和检验进行数据分析。
中药组临床痊愈率(81.8%)高于中西医结合组(54.8%),差异有统计学意义(P=0.02)。两组平均退热时间均为 3.5~4 天,差异无统计学意义(P=0.86)。中药组的中药费、西药费、治疗费和总费用均低于中西医结合组,差异有统计学意义(P=0.01、P=0.00、P=0.00、P=0.00)。
发热门诊甲型 H1N1 流感患者应用中药治疗的临床痊愈率高于中西医结合治疗,且费用更低。但由于中药组例数较少,结论尚需大样本研究进一步证实。