在西班牙塞维利亚分离出的淋病奈瑟菌菌株的抗生素耐药性、质粒图谱、营养型和血清型
Antibiotic resistance, plasmid profile, auxotypes and serovars of Neisseria gonorrhoeae strains isolated in Sevilla (Spain).
作者信息
Palomares J C, Lozano M C, Perea E J
机构信息
Department of Microbiology, School of Medicine, University of Sevilla, Spain.
出版信息
Genitourin Med. 1990 Apr;66(2):87-90. doi: 10.1136/sti.66.2.87.
Abstract
The antibiotics resistance pattern, the plasmid profile, the auxotypes and serotypes of 116 Neisseria gonorrhoeae clinical isolates obtained in one year were examined. The incidence of penicillinase producing (PPNG) strains was 12% (14 strains). The most frequent plasmid pattern was the combination of 4.5, 2.6 and 24.5 MDa plasmids. The conjugative plasmid of 24.5 MDa showed a high prevalence (32% of the total strains), and almost all the PPNG strains harboured this plasmid. The strains with the 4.5 MDa plasmid belonged to the auxotypes Pro-, Zero and Pro-Hyx-Ura-, whereas that with the 3.2 MDa plasmid was of auxotype Pro-Hyx-His-. The serotypes Aedih/Arst (WI serogroup) and Bak/Bropt, Back/Bropyt and Bak/Bropyt (WII/III serogroup) were predominant.
摘要
对一年内分离得到的116株淋病奈瑟菌临床分离株的抗生素耐药模式、质粒图谱、营养缺陷型和血清型进行了检测。产青霉素酶（PPNG）菌株的发生率为12%（14株）。最常见的质粒图谱是4.5、2.6和24.5 MDa质粒的组合。24.5 MDa的接合性质粒具有较高的流行率（占总菌株的32%），几乎所有PPNG菌株都携带该质粒。携带4.5 MDa质粒的菌株属于Pro-、Zero和Pro-Hyx-Ura-营养缺陷型，而携带3.2 MDa质粒的菌株属于Pro-Hyx-His-营养缺陷型。血清型Aedih/Arst（WI血清群）和Bak/Bropt、Back/Bropyt和Bak/Bropyt（WII/III血清群）占主导地位。
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