在阿姆斯特丹分离出的携带亚洲型质粒的产青霉素酶淋病奈瑟菌菌株的血清型、营养缺陷型和质粒图谱。

Serovars, auxotypes, and plasmid profiles of PPNG strains with Asian type plasmid isolated in Amsterdam.

作者信息

Ansink-Schipper M C, Bygdeman S M, van Klingeren B, Sandström E G

机构信息

Municipal Health Service, Amsterdam, The Netherlands.

出版信息

Genitourin Med. 1988 Jun;64(3):152-5. doi: 10.1136/sti.64.3.152.

DOI:10.1136/sti.64.3.152

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1194187/

Abstract

In 1982 an increase of penicillinase producing strains of Neisseria gonorrhoeae (PPNG), carrying the 4.5 megadalton Asian type plasmid and the 24 megadalton transfer plasmid (Asia+), was observed in Amsterdam. The main auxotypes were proline requiring (Pro-) and proline and hypoxanthine requiring (Pro-Hyx-). Using two monoclonal antibody systems, it was shown that the serovars of strains with these auxotypes isolated in 1981 were different from those isolated in 1982, which indicated the start and end of microepidemics. Different serovars were also observed in Pro- and non-requiring (NR) Asia- PPNG strains isolated in 1981-2 and 1985 respectively. Only one serovar (Aedih/Arst) was common in strains isolated in 1981-2 as well as in 1985.

摘要

1982年，在阿姆斯特丹观察到产青霉素酶淋病奈瑟菌（PPNG）菌株数量增加，这些菌株携带4.5兆达尔顿亚洲型质粒和24兆达尔顿转移质粒（Asia+）。主要营养缺陷型为脯氨酸需求型（Pro-）和脯氨酸及次黄嘌呤需求型（Pro-Hyx-）。使用两种单克隆抗体系统表明，1981年分离的具有这些营养缺陷型的菌株血清型与1982年分离的不同，这表明了微流行的开始和结束。在1981 - 1982年和1985年分别分离的Pro-和非需求型（NR）亚洲型PPNG菌株中也观察到不同的血清型。在1981 - 1982年以及1985年分离的菌株中只有一种血清型（Aedih/Arst）是共同的。

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Sex Transm Dis. 1987 Jan-Mar;14(1):26-32.

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Genetic studies on Neisseria gonorrhoeae from disseminated gonococcal infections.关于播散性淋球菌感染中淋病奈瑟菌的基因研究。

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