多重耐药鲍曼不动杆菌呼吸机相关性肺炎
Multi-drug resistant Acinetobacter ventilator-associated pneumonia.
作者信息
Shete Vishal B, Ghadage Dnyaneshwari P, Muley Vrishali A, Bhore Arvind V
机构信息
Department of Microbiology, BJ Medical College and Sassoon General Hospital, Pune, India.
出版信息
Lung India. 2010 Oct;27(4):217-20. doi: 10.4103/0970-2113.71952.
Abstract
BACKGROUND
Ventilator-associated pneumonia (VAP) due to a multi-drug resistant (MDR) Acinetobacter is one of the most dreadful complications, which occurs in the critical care setting.
AIMS AND OBJECTIVES
To find out the incidence of Acinetobacter infection in VAP cases, to determine various risk factors responsible for acquisition of Acinetobacter infection and to determine the antimicrobial susceptibility pattern of Acinetobacter.
MATERIALS AND METHODS
A total of 60 endotracheal aspirate specimens from intubated patients diagnosed clinically and microscopically as VAP were studied bacteriologically. All clinical details and prior exposure to antibiotics were recorded.
RESULTS
An incidence of 11.6% of Acinetobacter VAP cases was recorded. Various underlying conditions like head injury, cerebral hemorrhage and chronic obstructive pulmonary disease (COPD) were found to be associated with Acinetobacter VAP. Acinetobacter strains exhibited MDR pattern.
CONCLUSION
Strict infection control measures, judicious prescribing of antibiotics, antibiotic resistance surveillance programs and antibiotic cycling should be adopted to control infections due to these bacteria in patients admitted to intensive care units.
摘要
背景
由多重耐药不动杆菌引起的呼吸机相关性肺炎（VAP）是重症监护环境中最可怕的并发症之一。
目的
了解VAP病例中不动杆菌感染的发生率，确定导致不动杆菌感染的各种危险因素，并确定不动杆菌的抗菌药敏模式。
材料与方法
对60例临床和显微镜诊断为VAP的插管患者的气管内吸出物标本进行细菌学研究。记录所有临床细节和先前使用抗生素的情况。
结果
记录到不动杆菌VAP病例的发生率为11.6%。发现各种基础疾病如头部损伤、脑出血和慢性阻塞性肺疾病（COPD）与不动杆菌VAP有关。不动杆菌菌株呈现多重耐药模式。
结论
应采取严格的感染控制措施、合理使用抗生素、抗生素耐药监测计划和抗生素轮换，以控制重症监护病房患者中这些细菌引起的感染。
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