印度既往内脏利什曼病病例中杜氏利什曼原虫抗体的持续存在情况。
Persistence of Leishmania donovani antibodies in past visceral leishmaniasis cases in India.
作者信息
Gidwani Kamlesh, Picado Albert, Ostyn Bart, Singh Shri Prakash, Kumar Rajiv, Khanal Basudha, Lejon Veerle, Chappuis François, Boelaert Marleen, Sundar Shyam
机构信息
Banaras Hindu University, Varanasi, India.
出版信息
Clin Vaccine Immunol. 2011 Feb;18(2):346-8. doi: 10.1128/CVI.00473-10. Epub 2010 Dec 15.
Abstract
The persistence of anti-Leishmania donovani antibodies in past visceral leishmaniasis (VL) cases was retrospectively assessed by means of the direct agglutination test (DAT) and the rK39 enzyme-linked immunosorbent assay (ELISA). Antibody titers remained high for an extended period of time in past cases of VL. These results highlight the need to carefully elicit the history of patients with VL symptoms.
摘要
通过直接凝集试验（DAT）和rK39酶联免疫吸附测定（ELISA），对既往内脏利什曼病（VL）病例中抗杜氏利什曼原虫抗体的持续存在情况进行了回顾性评估。在既往VL病例中，抗体滴度在很长一段时间内一直保持较高水平。这些结果凸显了仔细询问有VL症状患者病史的必要性。
相似文献
1
Persistence of Leishmania donovani antibodies in past visceral leishmaniasis cases in India.印度既往内脏利什曼病病例中杜氏利什曼原虫抗体的持续存在情况。
Clin Vaccine Immunol. 2011 Feb;18(2):346-8. doi: 10.1128/CVI.00473-10. Epub 2010 Dec 15.
2
Evaluation of direct agglutination test, rk39 Test, and ELISA for the diagnosis of visceral leishmaniasis.评价直接凝集试验、rk39试验和酶联免疫吸附测定法用于内脏利什曼病的诊断。
Am J Trop Med Hyg. 2008 Jul;79(1):76-8.
3
Significantly lower anti-Leishmania IgG responses in Sudanese versus Indian visceral leishmaniasis.与印度内脏利什曼病相比，苏丹内脏利什曼病患者的抗利什曼原虫 IgG 反应明显降低。
PLoS Negl Trop Dis. 2014 Feb 20;8(2):e2675. doi: 10.1371/journal.pntd.0002675. eCollection 2014 Feb.
4
rK39 enzyme-linked immunosorbent assay for diagnosis of Leishmania donovani infection.用于诊断杜氏利什曼原虫感染的rK39酶联免疫吸附测定
Clin Diagn Lab Immunol. 1998 Sep;5(5):717-20. doi: 10.1128/CDLI.5.5.717-720.1998.
5
Latent infection with Leishmania donovani in highly endemic villages in Bihar, India.印度比哈尔邦高度流行地区利什曼原虫潜伏感染。
PLoS Negl Trop Dis. 2013;7(2):e2053. doi: 10.1371/journal.pntd.0002053. Epub 2013 Feb 14.
6
Serological markers for leishmania donovani infection in Nepal: Agreement between direct agglutination test and rK39 ELISA.尼泊尔利什曼原虫感染的血清学标志物：直接凝集试验和 rK39 ELISA 的一致性。
Trop Med Int Health. 2010 Nov;15(11):1390-4. doi: 10.1111/j.1365-3156.2010.02631.x.
7
8
Conversion of asymptomatic infection to symptomatic visceral leishmaniasis: A study of possible immunological markers.无症状感染向有症状内脏利什曼病的转化：对可能的免疫标志物的研究。
PLoS Negl Trop Dis. 2020 Jun 18;14(6):e0008272. doi: 10.1371/journal.pntd.0008272. eCollection 2020 Jun.
9
Diagnosing visceral leishmaniasis with the recombinant K39 strip test: experience from the Sudan.用重组K39试纸条检测法诊断内脏利什曼病：来自苏丹的经验。
Trop Med Int Health. 2001 Feb;6(2):108-13. doi: 10.1046/j.1365-3156.2001.00680.x.
10
rKLO8, a novel Leishmania donovani - derived recombinant immunodominant protein for sensitive detection of visceral leishmaniasis in Sudan.rKLO8，一种新型利什曼原虫衍生的重组免疫显性蛋白，可用于苏丹内脏利什曼病的敏感检测。
PLoS Negl Trop Dis. 2013 Jul 18;7(7):e2322. doi: 10.1371/journal.pntd.0002322. Print 2013.
引用本文的文献
1
Recombinant Leishmania-activated C kinase as a novel antigenic candidate for immuno-diagnosis of visceral leishmaniasis occurring in India and Brazil.重组利什曼原虫激活的C激酶作为印度和巴西内脏利什曼病免疫诊断的新型抗原候选物。
Infect Dis Poverty. 2025 Jul 9;14(1):62. doi: 10.1186/s40249-025-01296-7.
2
Direct agglutination test: Evolution and significance as a simple and safe alternative to tissue aspiration procedures in the diagnosis of visceral leishmaniasis.直接凝集试验：作为内脏利什曼病诊断中组织穿刺术的一种简单安全替代方法的演变及意义。
PLoS One. 2025 Jun 24;20(6):e0319118. doi: 10.1371/journal.pone.0319118. eCollection 2025.
3
The potential of Aurora kinase in the diagnosis of Indian and Brazilian visceral leishmaniasis patients.极光激酶在印度和巴西内脏利什曼病患者诊断中的潜力。
Microbiol Spectr. 2025 Jun 3;13(6):e0324724. doi: 10.1128/spectrum.03247-24. Epub 2025 Apr 16.
4
The development and maintenance of immunity against visceral leishmaniasis.针对内脏利什曼病免疫力的发展与维持。
Front Immunol. 2024 Dec 9;15:1486407. doi: 10.3389/fimmu.2024.1486407. eCollection 2024.
5
The immune response in canine and human leishmaniasis and how this influences the diagnosis- a review and assessment of recent research.犬和人利什曼病的免疫反应以及其对诊断的影响——对最新研究的回顾与评估。
Front Cell Infect Microbiol. 2023 Dec 8;13:1326521. doi: 10.3389/fcimb.2023.1326521. eCollection 2023.
6
Deletion of MIF gene from live attenuated LdCen parasites enhances protective CD4 T cell immunity.从减毒的 LdCen 寄生虫中删除 MIF 基因可增强保护性 CD4 T 细胞免疫。
Sci Rep. 2023 May 5;13(1):7362. doi: 10.1038/s41598-023-34333-2.
7
Immunoproteomics and phage display in the context of leishmaniasis complexity.免疫蛋白质组学和噬菌体展示在利什曼病复杂性方面的应用。
Front Immunol. 2023 Feb 8;14:1112894. doi: 10.3389/fimmu.2023.1112894. eCollection 2023.
8
Case report: Diagnosis of visceral leishmaniasis using metagenomic next-generation sequencing and bone marrow smear.病例报告：应用宏基因组下一代测序和骨髓涂片诊断内脏利什曼病。
Front Cell Infect Microbiol. 2022 Dec 23;12:1095072. doi: 10.3389/fcimb.2022.1095072. eCollection 2022.
9
ELISA-based evaluation of antibody response to Leishmania in a region endemic for cutaneous leishmaniasis.基于 ELISA 的方法评估利什曼原虫抗体反应在皮肤利什曼病流行地区。
Parasite Immunol. 2022 Sep;44(9):e12940. doi: 10.1111/pim.12940. Epub 2022 Aug 3.
10
Mediterranean visceral leishmaniasis : update on biological diagnosis.地中海内脏利什曼病：生物学诊断的最新进展。
Tunis Med. 2022;100(1):13-26.
本文引用的文献
1
Serological markers for leishmania donovani infection in Nepal: Agreement between direct agglutination test and rK39 ELISA.尼泊尔利什曼原虫感染的血清学标志物：直接凝集试验和 rK39 ELISA 的一致性。
Trop Med Int Health. 2010 Nov;15(11):1390-4. doi: 10.1111/j.1365-3156.2010.02631.x.
2
The epidemiology of Leishmania donovani infection in high transmission foci in India.印度高传播地区感染杜氏利什曼原虫的流行病学。
Trop Med Int Health. 2010 Jul;15 Suppl 2:12-20. doi: 10.1111/j.1365-3156.2010.02519.x. Epub 2010 May 6.
3
Immunobiology of leishmaniasis.利什曼病的免疫生物学
Indian J Exp Biol. 2009 Jun;47(6):412-23.
4
PCR and direct agglutination as Leishmania infection markers among healthy Nepalese subjects living in areas endemic for Kala-Azar.在生活在黑热病流行地区的健康尼泊尔人中，将聚合酶链反应（PCR）和直接凝集反应作为利什曼原虫感染标志物。
Trop Med Int Health. 2009 Apr;14(4):404-11. doi: 10.1111/j.1365-3156.2009.02242.x. Epub 2009 Feb 17.
5
Impact of amphotericin-B in the treatment of kala-azar on the incidence of PKDL in Bihar, India.两性霉素B治疗黑热病对印度比哈尔邦皮肤利什曼病发病率的影响。
Indian J Med Res. 2008 Jul;128(1):38-44.
6
Diagnostic tests for kala-azar: a multi-centre study of the freeze-dried DAT, rK39 strip test and KAtex in East Africa and the Indian subcontinent.黑热病的诊断测试：在东非和印度次大陆对冻干直接凝集试验、rK39试纸条检测和KAtex进行的多中心研究。
Trans R Soc Trop Med Hyg. 2008 Jan;102(1):32-40. doi: 10.1016/j.trstmh.2007.09.003. Epub 2007 Oct 22.
7
Comparative evaluation of freeze-dried and liquid antigens in the direct agglutination test for serodiagnosis of visceral leishmaniasis (ITMA-DAT/VL).冻干抗原与液体抗原在内脏利什曼病血清学诊断直接凝集试验（ITMA-DAT/VL）中的比较评估
Trop Med Int Health. 2006 Dec;11(12):1777-84. doi: 10.1111/j.1365-3156.2006.01743.x.
8
Immunologic tests in patients after clinical cure of visceral leishmaniasis.内脏利什曼病临床治愈后患者的免疫学检测。
Am J Trop Med Hyg. 2006 Oct;75(4):739-43.
9
Elimination of leishmaniasis (kala-azar) from the Indian subcontinent is technically feasible & operationally achievable.在印度次大陆消除利什曼病（黑热病）在技术上是可行的，在操作上也是可以实现的。
Indian J Med Res. 2006 Mar;123(3):195-6.
10
Serious underreporting of visceral leishmaniasis through passive case reporting in Bihar, India.印度比哈尔邦通过被动病例报告对内脏利什曼病的严重漏报情况。
Trop Med Int Health. 2006 Jun;11(6):899-905. doi: 10.1111/j.1365-3156.2006.01647.x.
Zotero 插件