土耳其爱琴海地区成年人的维生素 D 状况。
Vitamin D status among adults in the Aegean region of Turkey.
机构信息
Celal Bayar University Medical Faculty, Department of Internal Medicine, Division of Endocrinology and Metabolism, Manisa, Turkey.
出版信息
BMC Public Health. 2010 Dec 23;10:782. doi: 10.1186/1471-2458-10-782.
BACKGROUND
Vitamin D is a lipid-soluble hormone found in certain foods and synthesized from precursors in the skin when exposed to ultraviolet light. Vitamin D plays a critical role in bone metabolism and many cellular and immunological processes and low levels have been associated with several chronic and infectious diseases. Vitamin D status is assessed by measuring the concentration of serum 25-hydroxyvitamin D [25(OH)D]. Vitamin D deficiency is reported to be common worldwide, but little has been reported about the vitamin D status of adults in Turkey. In this cross-sectional study, we determined the prevalence of 25(OH)D deficiency in adults residing in a city in the Aegean region of Turkey.
METHODS
A survey was conducted on a representative sample of adults over 20 years old in a non-coastal city at the end of the winter season. Of the 209 households selected by random sampling, 8.6% (n = 18) were unoccupied and 21.5% (n = 45) refused to participate. Blood samples were taken and questions about medical history, vitamin supplementation, sunlight exposure, and dietary calcium and vitamin D intake were asked in face-to-face interviews of 391 adults living in the remaining households.
RESULTS
The mean serum 25(OH)D concentration was 16.9 ± 13.09 ng/mL, with 74.9% of the subjects having 25(OH)D deficiency (<20 ng/mL), 13.8% having insufficiency (20-29.99 ng/mL), and 11.3% of the subjects having sufficient 25(OH)D (≥ 30 ng/mL) levels. 25(OH)D deficiency was more common among females (78.7%) than males (66.4%, p < 0.05).
CONCLUSION
Adults living in an urban, non-coastal setting in Turkey have a high prevalence of vitamin D deficiency.
背景
维生素 D 是一种脂溶性激素，存在于某些食物中，并在皮肤暴露于紫外线下时从前体合成。维生素 D 在骨骼代谢和许多细胞及免疫过程中发挥着关键作用，其水平降低与多种慢性和感染性疾病相关。维生素 D 状态通过测量血清 25-羟维生素 D [25(OH)D] 的浓度来评估。据报道，维生素 D 缺乏在全球范围内很常见，但有关土耳其成年人维生素 D 状况的报道却很少。在这项横断面研究中，我们确定了居住在土耳其爱琴海地区城市的成年人中 25(OH)D 缺乏的流行率。
方法
在冬季结束时，对一个非沿海城市的成年代表性样本进行了一项调查。在通过随机抽样选择的 209 户家庭中，8.6%（n=18）为空置家庭，21.5%（n=45）拒绝参与。在剩余家庭中，对 391 名成年人进行了面对面访谈，采集了血液样本，并询问了病史、维生素补充、阳光照射以及膳食钙和维生素 D 摄入等问题。
结果
血清 25(OH)D 浓度的平均值为 16.9±13.09ng/mL，74.9%的受试者存在 25(OH)D 缺乏症（<20ng/mL），13.8%存在不足（20-29.99ng/mL），11.3%的受试者 25(OH)D 水平充足（≥30ng/mL）。女性（78.7%）比男性（66.4%）更常见 25(OH)D 缺乏症（p<0.05）。
结论
居住在土耳其城市非沿海地区的成年人存在较高的维生素 D 缺乏症患病率。
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