San Jose Creek Water Quality Laboratory, Sanitation Districts of Los Angeles County, Whittier, CA 90601, USA.
Environ Sci Technol. 2011 Feb 15;45(4):1228-34. doi: 10.1021/es102452f. Epub 2010 Dec 28.
Hourly samples of tertiary wastewater effluent were analyzed for 30 pharmaceuticals, personal care products, estrogenic steroids, and alkylphenols in order to better understand the rate at which these compounds enter the environment. Several distinct patterns of daily cycling were observed, and were characterized as three separate categories. The concentrations of compounds such as trimethoprim, sulfamethoxazole, naproxen, estrone, and triclosan varied greatly during a daily cycle, with relative standard deviations exceeding 100% of their daily mean. Less extreme daily cycles were seen for other compounds such as azithromycin, atenolol, tert-octylphenol, iopromide and gemfibrozil. Peak concentrations for most compounds occurred in the early evening (5-8 pm). However, some compounds including carbamazepine, primidone, fluoxetine, and triclocarban exhibited little or no variability.
为了更好地了解这些化合物进入环境的速度，对三级废水处理厂的废水进行了每小时采样，以分析 30 种药物、个人护理产品、雌激素类固醇和烷基酚。观察到几种不同的日常循环模式，并将其特征化为三个不同的类别。三苯甲烷、磺胺甲恶唑、萘普生、雌酮和三氯生等化合物的浓度在一天的周期内变化很大，其相对标准偏差超过其日平均值的 100%。其他化合物如阿奇霉素、阿替洛尔、叔辛基酚、碘普罗胺和吉非贝齐的日循环则不那么极端。大多数化合物的峰值浓度出现在傍晚（下午 5 点至 8 点）。然而，一些化合物，包括卡马西平、苯巴比妥、氟西汀和三氯卡班，表现出很少或没有变化。
