Pediatric Department, Abuzar Children's Hospital, Ahvaz Jondishapour University of Medical Sciences, Golestan street, Ahvaz, Iran.
Ital J Pediatr. 2011 Jan 6;37:1. doi: 10.1186/1824-7288-37-1.
Obesity has been identified as a risk factor for higher prevalence of asthma and asthma-related symptoms in children. The objective of this study was to evaluate the relationship between the prevalence of asthma symptoms and obesity among school-age children in the city of Ahvaz, Iran.
A total of 903 children, 7 to 11 years of age, were enrolled in this study through cluster sampling. The International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire was used to identify the children who were currently suffering from asthma. Height and weight were measured and body mass index (BMI) was calculated in kg/m2. Overweight was defined as BMI greater than the age- and sex-specific 85th percentile, and obesity as BMI greater than the 95th percentile. We determined the relationship between obesity and asthma symptoms by chi-square tests.
The prevalence of wheeze ever, current wheezing, obesity, and overweight was 21.56%, 8.7%, 6.87%, and 9.5%, respectively. The current prevalence of wheezing among obese and overweight children was 68.75% and 37%, respectively, and there was a statistical association between obesity and the prevalence of current wheezing (p < 0.001), night cough (p < 0.001), and exercise-induced wheezing (p = 0.009), but obesity and overweight were not associated with eczema and allergic rhinoconjunctivitis, so it seems that the pathophysiology of asthma in obese and overweight children is not related to allergy.
There is a strong association between asthma symptoms and both overweight and obesity in both sexes among school-age children.
肥胖已被确定为儿童哮喘及相关症状高发的一个风险因素。本研究旨在评估伊朗阿瓦兹市学龄儿童哮喘症状与肥胖之间的关系。
采用整群抽样方法，共纳入 903 名 7 至 11 岁的儿童。采用国际儿童哮喘和过敏研究（ISAAC）问卷来确定当前患有哮喘的儿童。测量身高和体重，并计算体重指数（BMI），以 kg/m2 为单位。超重定义为 BMI 大于年龄和性别特异性第 85 百分位数，肥胖定义为 BMI 大于第 95 百分位数。通过卡方检验确定肥胖与哮喘症状之间的关系。
喘息发作史、当前喘息、肥胖和超重的患病率分别为 21.56%、8.7%、6.87%和 9.5%。肥胖和超重儿童当前喘息的患病率分别为 68.75%和 37%，肥胖与当前喘息（p<0.001）、夜间咳嗽（p<0.001）和运动诱发的喘息（p=0.009）的流行率之间存在统计学关联，但肥胖和超重与特应性皮炎和过敏性鼻结膜炎无关，因此肥胖和超重儿童哮喘的病理生理学似乎与过敏无关。
在学龄儿童中，无论性别，哮喘症状与超重和肥胖均密切相关。
