Computational Systems Biology Group, National Centre for Biotechnology (CNB-CSIC), Madrid, Spain.
Bioinformatics. 2011 Mar 1;27(5):730-1. doi: 10.1093/bioinformatics/btr001. Epub 2011 Jan 5.
While many tools exist for performing enrichment analysis of transcriptomic and proteomic data in order to interpret them in biological terms, almost no equivalent tools exist for metabolomic data. We present Metabolite Biological Role (MBRole), a web server for carrying out over-representation analysis of biological and chemical annotations in arbitrary sets of metabolites (small chemical compounds) coming from metabolomic data of any organism or sample.
The web server is freely available at http://csbg.cnb.csic.es/mbrole. It was tested in the main web browsers.
虽然有许多工具可用于对转录组学和蛋白质组学数据进行富集分析，以便从生物学角度解释这些数据，但几乎没有等效的工具可用于代谢组学数据。我们介绍了代谢物生物学作用（MBRole），这是一个网络服务器，可用于对来自任何生物体或样本的代谢组学数据中任意代谢物（小分子化合物）集的生物学和化学注释进行过表达分析。
该网络服务器可免费在 http://csbg.cnb.csic.es/mbrole 获得。它已在主流网络浏览器中进行了测试。
