Department of Ophthalmology, Gulhane Military Medical Academy, Ankara, Turkey.
Cornea. 2011 Jun;30(6):670-4. doi: 10.1097/ICO.0b013e31820128a4.
Measurement of central corneal thickness (CCT) plays an essential role in the diagnosis and treatment of many ocular diseases. In this study, we aimed to compare the CCT measurements obtained using the Scheimpflug system (Pentacam; Oculus, Inc) with a retinal optical coherence tomography device (Stratus OCT; Carl Zeiss Meditec, Inc) to examine healthy corneas.
CCT measurements of 80 eyes belonging to 40 male patients (mean age: 24.48 ± 6.01 years) were evaluated with the Pentacam and the Stratus OCT. The relationship between the CCT values obtained with these 2 devices was examined with a Pearson correlation analysis, a paired t test, and a Bland-Altman analysis.
The average CCT value obtained with Pentacam was 546.11 ± 34.15 μm and that obtained with Stratus OCT was 567.76 ± 35.02 μm. Although the average difference between the devices was 21.65 ± 8.59 μm (P < 0.0001), the measurements obtained with both devices were significantly correlated (r = 0.969, P < 0.0001). In Bland-Altman analysis, there was a high consistency between measurements obtained with either Pentacam or Stratus OCT devices.
Corneal thickness measurements differ depending on the device used. Corneal thicknesses that have been calculated with Pentacam were lower than the values obtained with Stratus OCT. Both devices used for CCT measurement are easily applied, noninvasive, and effective. However, the devices are not interchangeable. Stratus OCT is not optimal for CCT measurement because of the important limitations of using manual measurements, but it can be used if other measurement devices designed for the purpose are not available.
中央角膜厚度（CCT）的测量在许多眼病的诊断和治疗中起着至关重要的作用。本研究旨在比较使用Scheimpflug 系统（Pentacam；Oculus，Inc）和视网膜光学相干断层扫描设备（Stratus OCT；Carl Zeiss Meditec，Inc）测量健康角膜的 CCT 结果。
对 40 名男性患者（平均年龄：24.48±6.01 岁）的 80 只眼进行了 Pentacam 和 Stratus OCT 的 CCT 测量。使用 Pearson 相关分析、配对 t 检验和 Bland-Altman 分析评估了这两种设备获得的 CCT 值之间的关系。
Pentacam 获得的平均 CCT 值为 546.11±34.15μm，Stratus OCT 获得的平均 CCT 值为 567.76±35.02μm。虽然两种设备之间的平均差异为 21.65±8.59μm（P<0.0001），但两种设备的测量值均呈显著相关性（r=0.969，P<0.0001）。在 Bland-Altman 分析中，两种设备的测量值之间具有高度一致性。
使用不同的设备测量角膜厚度会有差异。使用 Pentacam 计算的角膜厚度值低于 Stratus OCT 获得的值。两种用于 CCT 测量的设备均易于操作、非侵入性且有效。然而，这些设备不能互换。Stratus OCT 因其手动测量的重要限制而不适用于 CCT 测量，但如果没有专门设计用于 CCT 测量的其他测量设备，则可以使用。
