Department of Public and Occupational Health, EMGO Institute for Health and Care Research, VU University Medical Center, 1007 MB Amsterdam, the Netherlands.
Scand J Work Environ Health. 2011 Jul;37(4):263-75. doi: 10.5271/sjweh.3143. Epub 2011 Jan 18.
This systematic review aims to summarize the available evidence to elucidate the effects of shift work, which includes night work, on body weight change.
A systematic search strategy using longitudinal studies was performed. Articles were included based on strict inclusion criteria; methodological quality was assessed by a standardized quality checklist. The results were summarized using a levels of evidence synthesis.
The search strategy resulted in eight articles that met the inclusion criteria. Five of them were considered to be high- and three of them low-quality studies. Seven studies presented crude results for an association between shift work exposure and change in body weight: five high- and two low-quality studies. There was strong evidence for a crude relationship between shift work and body weight increase. Five studies presented weight-related outcomes adjusted for potentially relevant confounders (age, gender, bodyweight at baseline, and physical activity). Two studies found a significant difference between groups in the same direction. Consequently, the evidence for a confounders-adjusted relationship between shift work exposure and body weight was considered to be insufficient.
Strong evidence for a crude association between shift work exposure and body weight increase was found. In order to further clarify the underlying mechanisms, more and better high quality studies about this subject are necessary.
本系统评价旨在总结现有证据，阐明轮班工作（包括夜班）对体重变化的影响。
采用纵向研究的系统检索策略。根据严格的纳入标准纳入文章；使用标准化质量检查表评估方法学质量。使用证据水平综合来总结结果。
搜索策略产生了 8 篇符合纳入标准的文章。其中 5 篇被认为是高质量研究，3 篇是低质量研究。7 项研究报告了轮班工作暴露与体重变化之间的关联的原始结果：5 项高质量研究和 2 项低质量研究。轮班工作与体重增加之间存在强烈的关联。5 项研究根据潜在相关混杂因素（年龄、性别、基线体重和体力活动）调整了与体重相关的结果。两项研究发现两组之间存在相同方向的显著差异。因此，认为轮班工作暴露与体重之间的调整混杂因素关系的证据不足。
发现轮班工作暴露与体重增加之间存在强烈的关联。为了进一步阐明潜在的机制，需要更多和更好的关于这一主题的高质量研究。
