Department of Nephrology, School of Medicine, University of Thessaly, Larissa, Greece.
ASAIO J. 2010 Nov-Dec;56(6):538-42. doi: 10.1097/MAT.0b013e3181f1cc04.
Restless legs syndrome (RLS) is very common in hemodialysis patients. RLS induces motor excitability and discomfort during rest periods, and those symptoms have also been observed during hemodialysis sessions. The aim of the study was to assess whether a single bout of exercise could reduce periodic limb movements (PLM) occurring during hemodialysis. Eighteen hemodialysis patients were eligible and participated in the study. Using the RLS criteria and further verified by the presence of PLM during sleep, patients were divided to non-RLS and RLS groups. Three scenarios were studied during three different sessions: 1) light exercise, including cycling for 45 minutes with no added resistance, 2) heavy exercise, including cycling for 45 minutes with a resistance set at 60% of their exercise capacity, and 3) no exercise, including rest for the same period of time. In all sessions, PLM per hour of hemodialysis (PLM/hHD) was recorded. A single bout of either light or heavy exercise was equally effective in significantly reducing PLM/hHD in patients with RLS compared with the no-exercise scenario, whereas in non-RLS patients, no effect was observed. Independent of intensity, a single bout of intradialytic exercise reduces PLM/hHD in hemodialysis patients with RLS. Further research is needed to establish the acute role of exercise in ameliorating the RLS symptoms.
不宁腿综合征（RLS）在血液透析患者中非常常见。RLS 在休息期间引起运动兴奋性和不适，这些症状在血液透析期间也观察到。本研究的目的是评估单次运动是否可以减少血液透析期间发生的周期性肢体运动（PLM）。18 名血液透析患者符合条件并参加了研究。使用 RLS 标准并通过睡眠期间存在 PLM 进一步验证，将患者分为非 RLS 和 RLS 组。在三个不同的会话中研究了三种情况：1）轻度运动，包括骑自行车 45 分钟，不增加阻力，2）剧烈运动，包括骑自行车 45 分钟，阻力设置为其运动能力的 60%，3）无运动，包括相同时间的休息。在所有会话中，记录每小时血液透析的周期性肢体运动（PLM/hHD）。与无运动情景相比，单次轻或重运动在 RLS 患者中同样有效地显著减少 PLM/hHD，而在非 RLS 患者中则没有观察到这种效果。无论强度如何，单次血液透析内运动均可减少 RLS 患者的 PLM/hHD。需要进一步研究以确定运动在改善 RLS 症状方面的急性作用。
