Department of Odontostomatological, Orthodontic and Surgical Sciences, Second University of Naples, Via De Crecchio 6, Naples, Italy.
Int J Oral Maxillofac Surg. 2011 May;40(5):526-32. doi: 10.1016/j.ijom.2010.12.005. Epub 2011 Feb 1.
After tooth extraction the healing process involves bone resorption and soft tissue contraction, events that can compromise the ideal implant placement with functional and aesthetic limitations. Following tooth extraction, a socket preservation technique can limit bone resorption. This study evaluated two different types of hydroxyapatite (HA) grafting materials placed into fresh extraction sockets, 6 months after tooth extraction, histologically, clinically and radiographically. Ten extraction sockets from 10 patients were divided in two groups: 5 sockets received a biomimetic HA and 5 received nanocrystalline HA. After 6 months, before implant placement, samples from the grafted area were harvested and evaluated clinically, radiographically and histologically. The percentages of bone, osteoid areas and residual material in the two groups were not statistically different. All samples showed great variability with extensive bone formation and total material resorption or amounts of osteoid tissue that filled the spaces between the residual material particles. The authors did not find any differences between biomimetic and nanocrystalline HA and assume that, within the limits of this study, both these materials could be applied into fresh extraction sockets to limit bone resorption. A control material and a much larger sample size are needed to confirm these findings.
拔牙后，愈合过程涉及骨吸收和软组织收缩，这些事件可能会影响理想的种植体植入位置，导致功能和美学受限。拔牙后，采用窝洞保存技术可以限制骨吸收。本研究通过组织学、临床和影像学评估了两种不同类型的羟基磷灰石（HA）移植材料在拔牙后 6 个月时被放置在新鲜拔牙窝中的情况。10 名患者的 10 个拔牙窝被分为两组：5 个拔牙窝接受仿生 HA，5 个拔牙窝接受纳米 HA。6 个月后，在植入种植体之前，从移植区域采集样本并进行临床、放射学和组织学评估。两组的骨、类骨质区域和残留材料的百分比没有统计学差异。所有样本都显示出很大的变异性，表现为广泛的骨形成和完全的材料吸收，或类骨质组织填充残留材料颗粒之间的空间。作者没有发现仿生 HA 和纳米 HA 之间有任何差异，并假设在本研究的范围内，这两种材料都可以应用于新鲜拔牙窝以限制骨吸收。需要对照材料和更大的样本量来证实这些发现。
