Department of Pediatrics, Oslo University Hospital, Ullevaal, 0407 Oslo, Norway.
Pediatr Res. 2011 May;69(5 Pt 1):413-7. doi: 10.1203/PDR.0b013e31821267d2.
Long-term EEG monitoring (LTM) with several electrodes could be a useful tool for surveillance of the brain during the first critical days of life. This study aimed to assess the feasibility of multichannel LTM for automated analysis of EEG activity from d 1 to 3 using eight electrodes. Premature infants (GA <31 wk; n = 48) were continuously monitored for 3 d. EEG monitoring for a total of 3257 h was successfully performed. Total absolute band power (tABP) was calculated per second. Artifacts were removed visually or by an algorithm removing the highest 5, 10, 15, and 20% tABPs. NS difference was found between the trends of visually edited and 5% mathematically trimmed data. Two groups were compared (24 ≤ GA < 28 wk and 28 ≤ GA < 31 wk) using the median of tABP for all frequency bands per day. The results showed that tABP differed between groups. The changes of tABP d 1-3 were equal in both groups. Automatically assessed LTM confirms that the EEG activity depends on GA. However, it reveals that the early changes (d 1-3) are independent of GA. The study demonstrates the feasibility of multichannel LTM and the possibility of developing automated EEG analyses.
长期脑电图监测 (LTM) 结合多个电极可以成为生命最初关键几天内监测大脑的有用工具。本研究旨在评估使用 8 个电极从第 1 天到第 3 天对 EEG 活动进行自动分析的多通道 LTM 的可行性。对 48 名早产儿（GA <31 周）进行了 3 天的连续监测。成功完成了总共 3257 小时的 EEG 监测。每秒计算总绝对频带功率 (tABP)。通过视觉或通过去除最高 5%、10%、15%和 20% tABP 的算法去除伪影。在视觉编辑和 5%数学修剪数据的趋势之间发现了 NS 差异。使用每天所有频带的 tABP 中位数比较了两组（24 ≤ GA < 28 周和 28 ≤ GA < 31 周）。结果表明 tABP 在组间存在差异。两组的 tABP 变化在第 1-3 天相同。自动评估的 LTM 证实 EEG 活动取决于 GA。然而，它表明早期变化（d 1-3）与 GA 无关。该研究证明了多通道 LTM 的可行性以及开发自动 EEG 分析的可能性。
