Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD 21287, USA.
Am J Ophthalmol. 2011 May;151(5):850-7. doi: 10.1016/j.ajo.2010.10.039. Epub 2011 Feb 17.
To evaluate the physical functioning of Ethiopian trichiasis surgery patients before and 6 months after surgery.
Nested cohort study.
This study was nested within the Surgery for Trichiasis, Antibiotics to Prevent Recurrence (STAR) clinical trial conducted in Ethiopia. Demographic information, ocular examinations, and physical functioning assessments were collected before and 6 months after surgery. A single score for patients' physical functioning was constructed using Rasch analysis. A multivariate linear regression model was used to determine if change in physical functioning was associated with change in visual acuity.
Of the 438 participants, 411 (93.8%) had both baseline and follow-up questionnaires. Physical functioning scores at baseline ranged from -6.32 (great difficulty) to +6.01 (no difficulty). The percentage of participants reporting no difficulty in physical functioning increased by 32.6%; the proportion of participants in the mild/no visual impairment category increased by 8.6%. A multivariate linear regression model showed that for every line of vision gained, physical functioning improves significantly (0.09 units; 95% CI: 0.02-0.16).
Surgery to correct trichiasis appears to improve patients' physical functioning as measured at 6 months. More effort in promoting trichiasis surgery is essential, not only to prevent corneal blindness, but also to enable improved functioning in daily life.
评估埃塞俄比亚倒睫手术患者手术前后的身体机能。
嵌套队列研究。
本研究嵌套在埃塞俄比亚进行的《倒睫手术,抗生素预防复发(STAR)》临床试验中。在手术前后收集人口统计学信息、眼部检查和身体机能评估。使用 Rasch 分析为患者的身体机能构建单一评分。使用多变量线性回归模型来确定身体机能的变化是否与视力变化相关。
在 438 名参与者中,有 411 名(93.8%)同时具有基线和随访问卷。基线时身体机能评分范围为-6.32(极度困难)至+6.01(无困难)。报告身体机能无障碍的参与者比例增加了 32.6%;轻度/无视力障碍类别的参与者比例增加了 8.6%。多变量线性回归模型显示,每提高一行视力,身体机能就会显著改善(0.09 单位;95%CI:0.02-0.16)。
纠正倒睫的手术似乎可以改善患者在术后 6 个月的身体机能。需要更加努力地推广倒睫手术,不仅可以预防角膜盲,还可以提高日常生活中的功能。