Childhood Cancer Research Group, University of Oxford, Oxford, UK.
Leuk Res. 2011 Aug;35(8):1039-43. doi: 10.1016/j.leukres.2011.01.023. Epub 2011 Feb 21.
Natural sources contribute a large fraction of the radiation exposure of the general public. Under the linear no-threshold hypothesis risk decreases in proportion to decreasing dose without a threshold. We use recent estimates of doses to the red bone marrow to calculate the number and proportion of cases of leukemia in England induced by natural radiation. We calculate that about 5% of cases of leukemia, excluding chronic lymphocytic leukemia, up to the age of 80 years are induced by this background radiation. In young people up to the age of 25 years the attributable fraction is about 15%, substantially lower than a previous estimate.
天然辐射源是公众所受辐射照射的一个重要组成部分。在线性无阈假设下,风险随剂量的降低而呈比例降低,且不存在阈剂量。我们利用近期对红骨髓剂量的估算结果,计算了在英格兰因天然辐射而诱发的白血病病例数和比例。我们计算出,在 80 岁以下的人群中,除慢性淋巴细胞白血病外,约有 5%的白血病病例是由这种本底辐射引起的。在 25 岁以下的年轻人中,归因分数约为 15%,明显低于以前的估计值。