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EQ-5D对急性冠状动脉综合征患者而言是一种有效的生活质量评估工具吗?

Is EQ-5D a valid quality of life instrument in patients with acute coronary syndrome?

作者信息

Kahyaoğlu Süt Hatice, Unsar Serap

机构信息

Department of Nursing, Health Sciences Institute, Faculty of Health Sciences, Trakya University, Edirne, Turkey.

出版信息

Anadolu Kardiyol Derg. 2011 Mar;11(2):156-62. doi: 10.5152/akd.2011.037. Epub 2011 Feb 23.

DOI:10.5152/akd.2011.037
PMID:21342862
Abstract

OBJECTIVE

To evaluate the construct validity of the Turkish version of the EQ-5D in patients with acute coronary syndrome.

METHODS

The study was conducted as a cross-sectional study at the Trakya University Hospital between February and May 2008. All patients completed the Turkish version of the EQ-5D and MacNew heart-related quality of life scale. Construct validity of the EQ-5D was assessed according to relationships with MacNew subscales by using Spearman rank correlation and multiple linear regression analyses.

RESULTS

One hundred and twenty-two patients responded to the instruments. Mean age was 62.9±9.3 years and male gender (88 or 72.1%) was dominant. Mean score of the EQ-5D index was 0.79±0.32, while the global score of MacNew was 5.01±1.16. The correlation coefficients of the EQ-5D index score with the MacNew subscales ranged from 0.557 to 0.721, with EQ-5D VAS score ranging from 0.297 to 0.484 (p<0.001 for all of them). According to the stepwise regression model MacNew global score was found to be significantly effective factor on EQ-5D index score (β =0.188; 95% CI: 0.152-0.224; p<0.001).

CONCLUSION

The Turkish version of the EQ-5D-based utility score seems to be a valid instrument in the assessment of quality of life studies in patients with acute coronary syndrome.

摘要

目的

评估急性冠状动脉综合征患者中EQ - 5D土耳其语版本的结构效度。

方法

该研究于2008年2月至5月在恰纳卡莱奥森克兹马尔特大学医院作为横断面研究进行。所有患者均完成了EQ - 5D土耳其语版本和MacNew心脏相关生活质量量表。通过使用Spearman等级相关和多元线性回归分析,根据与MacNew子量表的关系评估EQ - 5D的结构效度。

结果

122名患者对这些工具做出了回应。平均年龄为62.9±9.3岁,男性占主导(88名或72.1%)。EQ - 5D指数的平均得分为0.79±0.32,而MacNew的总体得分为5.01±1.16。EQ - 5D指数得分与MacNew子量表的相关系数范围为0.557至0.721,EQ - 5D视觉模拟量表(VAS)得分范围为0.297至0.484(所有p值均<0.001)。根据逐步回归模型,发现MacNew总体得分是EQ - 5D指数得分的显著有效因素(β =0.188;95%置信区间:0.152 - 0.224;p<0.001)。

结论

基于EQ - 5D的土耳其语版本效用得分似乎是评估急性冠状动脉综合征患者生活质量研究的有效工具。

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