Internal Medicine, Institut Jules Bordet, Brussels, Belgium.
Osteoporos Int. 2011 Nov;22(11):2769-88. doi: 10.1007/s00198-011-1545-x. Epub 2011 Mar 1.
This consensus article reviews the various aspects of the non-pharmacological management of osteoporosis, including the effects of nutriments, physical exercise, lifestyle, fall prevention, and hip protectors. Vertebroplasty is also briefly reviewed. Non-pharmacological management of osteoporosis is a broad concept. It must be viewed as an essential part of the prevention of fractures from childhood through adulthood and the old age. The topic also includes surgical procedures for the treatment of peripheral and vertebral fractures and the post-fracture rehabilitation. The present document is the result of a consensus, based on a systematic review and a critical appraisal of the literature. Diets deficient in calcium, proteins or vitamin D impair skeletal integrity. The effect of other nutriments is less clear, although an excessive consumption of sodium, caffeine, or fibres exerts negative effects on calcium balance. The deleterious effects of tobacco, excessive alcohol consumption and a low BMI are well accepted. Physical activity is of primary importance to reach optimal peak bone mass but, if numerous studies have shown the beneficial effects of various types of exercise on bone mass, fracture data as an endpoint are scanty. Fall prevention strategies are especially efficient in the community setting, but less evidence is available about their effectiveness in preventing fall-related injuries and fractures. The efficacy of hip protectors remains controversial. This is also true for vertebroplasty and kyphoplasty. Several randomized controlled studies had reported a short-term advantage of vertebroplasty over medical treatment for pain relief, but these findings have been questioned by recent sham-controlled randomized clinical studies.
这篇共识文章回顾了骨质疏松症非药物治疗的各个方面,包括营养物质、体育锻炼、生活方式、跌倒预防和髋部保护器的作用。椎体成形术也进行了简要回顾。骨质疏松症的非药物治疗是一个广泛的概念。它必须被视为预防儿童期到成年期和老年期骨折的重要组成部分。该主题还包括治疗周围和脊柱骨折以及骨折后康复的手术程序。本文件是基于系统回顾和文献评价的共识结果。饮食中钙、蛋白质或维生素 D 缺乏会损害骨骼完整性。其他营养素的作用不太清楚,尽管钠、咖啡因或纤维的过量摄入对钙平衡有负面影响。烟草、过量饮酒和低 BMI 的有害影响是公认的。身体活动对于达到最佳峰值骨量至关重要,但尽管许多研究表明各种类型的运动对骨量有有益的影响,但作为终点的骨折数据却很少。跌倒预防策略在社区环境中特别有效,但关于其预防跌倒相关伤害和骨折的有效性的证据较少。髋部保护器的疗效仍存在争议。椎体成形术和后凸成形术也是如此。几项随机对照研究报告称,椎体成形术在缓解疼痛方面优于药物治疗,但最近的假对照随机临床试验对这些发现提出了质疑。