Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan.
Mycopathologia. 2011 Aug;172(2):131-9. doi: 10.1007/s11046-011-9408-8. Epub 2011 Mar 3.
The opportunistic Candida species existing as part of commensal microbiota in humans are usually the etiological agents causing infections. We investigated whether isolates collected from different age groups, hospital units, and sources have distinct characteristics. A total of 913 isolates comprising 395 Candida albicans, 230 Candida tropicalis, 202 Candida glabrata, 62 Candida parapsilosis, 13 Candida krusei, and 11 of other six species were analyzed. Urine was the most common source (41.2%), followed by sputum (16.3%), blood (15.2%), and others (27.3%). Candida albicans and C. parapsilosis were more prevalent in the working group [from 19 to 65 years], whereas C. tropicalis and C. glabrata were more prevalent in the elder one (≥ 66 years). We found that the age of patients and the source of isolates affect the distribution of species. On the other hand, the drug susceptibility of isolates was associated with fungal species and whether patients were hospitalized.
机会性念珠菌物种作为人类共生微生物群落的一部分，通常是引起感染的病原体。我们研究了来自不同年龄组、医院科室和来源的分离株是否具有不同的特征。共分析了 913 株分离株，包括 395 株白色念珠菌、230 株热带念珠菌、202 株光滑念珠菌、62 株近平滑念珠菌、13 株克柔念珠菌和其他 6 个种的 11 株。尿液是最常见的来源（41.2%），其次是痰（16.3%）、血液（15.2%）和其他（27.3%）。白色念珠菌和近平滑念珠菌在工作组（19-65 岁）中更为常见，而热带念珠菌和光滑念珠菌在老年组（≥66 岁）中更为常见。我们发现患者的年龄和分离株的来源影响了物种的分布。另一方面，分离株的药敏性与真菌种类和患者是否住院有关。
