Departments of Ophthalmology, Bascom Palmer Eye Institute, Jacksonville, Florida, USA.
Invest Ophthalmol Vis Sci. 2011 Jun 9;52(7):4091-7. doi: 10.1167/iovs.10-6507.
To characterize the edge fitting of soft contact lenses using ultra-high resolution optical coherence tomography (UHR-OCT) and ultra-long scan depth optical coherence tomography (UL-OCT).
A total of 20 participants (11 men, 9 women; mean age, 32.3 years) were recruited. Four different types of soft contact lenses were randomly fitted to both eyes of each subject on two separate visits. After 30 minutes, the horizontal meridians of the corneal center, midperiphery, and limbus were imaged by UHR-OCT. UL-OCT imaged each lens in vitro and the ocular surface of a physical model eye.
Angle-edged lenses had significantly less conjunctival buildup than did round-edged lenses (P = 0.008). Limbal post-lens tear film gaps were present in 42% of the eyes, with the round-edged lenses having the most at 68%. Similarly, post-lens tear film gaps at the corneal mid-periphery were present in 47% of all eyes, with the round-edged lens having the most at 75%. Mismatches between the lens and the ocular surface were simulated based on UL-OCT images of the in vitro lenses and the model eye. The existence of tear film gaps and touching points were predicted in the simulation.
The soft contact lens edge fitting was characterized by the conjunctival buildup and tear film gaps. Different types of contact lenses presented different levels of conjunctival buildup as well as different frequencies of tear film gaps. The findings by UHR-OCT were predicted in the simulation by UL-OCT. The application of these new technologies may open new ways of designing lenses and evaluating their fit.
使用超高清光学相干断层扫描(UHR-OCT)和超长扫描深度光学相干断层扫描(UL-OCT)对软镜边缘拟合进行特征描述。
共招募 20 名参与者(男 11 名,女 9 名;平均年龄 32.3 岁)。在两次不同的访问中,将四种不同类型的软镜随机适配于每位受试者的双眼。30 分钟后,使用 UHR-OCT 对角膜中心、中周和角膜缘的水平子午线进行成像。UL-OCT 对每片镜片进行体外成像,并对物理模型眼的眼表进行成像。
边缘角的镜片比边缘圆的镜片的结膜堆积明显少(P=0.008)。42%的眼睛存在边缘后镜片泪膜间隙,圆形边缘的眼睛最多,为 68%。同样,所有眼睛中有 47%存在角膜中周后的泪膜间隙,圆形边缘的眼睛最多,为 75%。根据体外镜片和模型眼的 UL-OCT 图像模拟了镜片和眼表之间的不匹配。在模拟中预测了泪膜间隙和接触点的存在。
软镜边缘拟合通过结膜堆积和泪膜间隙来描述。不同类型的隐形眼镜呈现不同程度的结膜堆积和不同频率的泪膜间隙。UHR-OCT 的发现通过 UL-OCT 的模拟进行了预测。这些新技术的应用可能为设计镜片和评估其适配性开辟新途径。