Blood Borne Virus Unit, Virus Reference Department, Centre for Infections, Health Protection Agency, London, UK.
Vox Sang. 2011 Apr;100(3):340-2. doi: 10.1111/j.1423-0410.2010.01412.x. Epub 2010 Sep 24.
The risk of hepatitis E virus (HEV) to blood safety remains unknown in England. Reports of persistent HEV infection with serious disease sequelae indicate that transfusion transmitted HEV is not a trivial disease in immunosuppressed patients.
Samples from unselected blood donors and donors with a history of jaundice were tested for HEV antibody and RNA.
Overall, 10% of the donor sera were anti-HEV IgG reactive. Four of the donor samples were anti-HEV IgM reactive but HEV RNA negative.
There is evidence of probable recent HEV infections in donors with a predicted attack rate of 2.8%.
在英国，戊型肝炎病毒（HEV）对血液安全的风险尚不清楚。有报道称，持续性 HEV 感染可导致严重的疾病后遗症，这表明对于免疫抑制患者来说，输血传播的 HEV 并非一种轻微疾病。
对未筛选的献血者和有黄疸病史的献血者的样本进行了戊型肝炎病毒抗体和 RNA 检测。
总的来说，10%的供者血清对 HEV 抗体 IgG 呈反应性。有 4 份供者样本对 HEV IgM 呈反应性，但 HEV RNA 为阴性。
有证据表明，在预计发病率为 2.8%的供者中存在近期 HEV 感染。
