Centre for Evidence Based Veterinary Medicine, School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Loughborough LE12 5RD, United Kingdom.
Prev Vet Med. 2011 May 1;99(2-4):185-92. doi: 10.1016/j.prevetmed.2011.02.009. Epub 2011 Mar 21.
Diarrhoea is a common and multi-factorial condition in dogs, the aetiology of which is often incompletely understood. A case-control study was carried out to compare the carriage of some common canine enteric pathogens (enteric coronavirus, parvovirus, distemper, endoparasites, Campylobacter and Salmonella spp.), as well as lifestyle factors such as vaccination history, diet and contact with other species, in dogs presenting at first opinion veterinary practices with and without diarrhoea. Multivariable conditional logistic regression showed that dogs in the study which scavenged or had had a recent change of diet (OR 3.5, p=0.002), had recently stayed in kennels (OR 9.5, p=0.01), or were fed a home-cooked diet (OR 4, p=0.002) were at a significantly greater risk of diarrhoea, whilst being female (OR 0.4, p=0.01), currently up to date with routine vaccinations (OR 0.4, p=0.05) and having contact with horse faeces (OR 0.4, p=0.06) were associated with a reduced risk. None of the pathogens tested for was a significant factor in the final multivariable model suggesting that in this predominantly vaccinated population, diarrhoea may be more associated with lifestyle risk factors than specific pathogens.
腹泻是犬的一种常见且多因素的病症，其病因通常不完全清楚。进行了一项病例对照研究，以比较在首次就诊的兽医诊所中出现腹泻和无腹泻的犬携带一些常见的犬肠病原体（肠冠状病毒、细小病毒、犬瘟热、内寄生虫、弯曲杆菌和沙门氏菌属）以及生活方式因素，如疫苗接种史、饮食和与其他物种的接触。多变量条件逻辑回归显示，在研究中，捡拾食物或最近改变饮食的犬（OR 3.5，p=0.002）、最近在犬舍逗留（OR 9.5，p=0.01）或喂食家庭自制饮食的犬（OR 4，p=0.002）患腹泻的风险显著增加，而雌性（OR 0.4，p=0.01）、当前常规疫苗接种及时（OR 0.4，p=0.05）和接触马粪便（OR 0.4，p=0.06）则与降低的风险相关。在最终的多变量模型中，未检测到的任何病原体都是一个重要因素，这表明在这个主要接种疫苗的人群中，腹泻可能与生活方式风险因素的关系更密切，而不是与特定病原体有关。
