Department of Pharmacology and Physiology, University of Rochester School of Medicine and Dentistry, NY, USA.
Libyan J Med. 2010 Nov 8;5. doi: 10.3402/ljm.v5i0.5648.
Over the past 2 years there has been a radical change in standard clinical practice with respect to vitamin D. As a result of a growing body of knowledgeable physicians are assessing the vitamin D nutritional status of their patients and prescribing aggressive repletion regimens of a vitamin D supplement. The present paper summarizes some basic information about this essential nutrient and reviews some of the more recent data implicating vitamin D deficiency in disease etiology with an emphasis on cardiovascular disease and cancer. Finally a rational approach to the dosing of vitamin D in different patient populations is provided.
在过去的 2 年中，维生素 D 的临床实践标准发生了根本性的变化。由于越来越多的医生了解到这一情况，他们开始评估患者的维生素 D 营养状况，并开出补充维生素 D 的强化方案。本文总结了有关这种必需营养素的一些基本知识，并回顾了一些最近的数据，这些数据表明维生素 D 缺乏与疾病的病因有关，重点是心血管疾病和癌症。最后，本文提供了针对不同患者人群补充维生素 D 的合理方法。
