• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
MicroRNA links obesity and impaired glucose metabolism.微小RNA将肥胖与葡萄糖代谢受损联系起来。
Cell Res. 2011 Jun;21(6):864-6. doi: 10.1038/cr.2011.78. Epub 2011 May 10.
2
MicroRNA-26a regulates insulin sensitivity and metabolism of glucose and lipids.微小RNA-26a调节胰岛素敏感性以及葡萄糖和脂质代谢。
J Clin Invest. 2015 Jun;125(6):2497-509. doi: 10.1172/JCI75438. Epub 2015 May 11.
3
Epigenetic contribution to obesity.肥胖的表观遗传学贡献。
Mamm Genome. 2020 Jun;31(5-6):134-145. doi: 10.1007/s00335-020-09835-3. Epub 2020 Apr 11.
4
Obesity upregulates genes involved in oxidative phosphorylation in livers of diabetic patients.肥胖会使糖尿病患者肝脏中参与氧化磷酸化的基因上调。
Obesity (Silver Spring). 2008 Dec;16(12):2601-9. doi: 10.1038/oby.2008.419. Epub 2008 Oct 9.
5
The microRNA-29 Family Dictates the Balance Between Homeostatic and Pathological Glucose Handling in Diabetes and Obesity.微小RNA-29家族决定糖尿病和肥胖症中稳态与病理性葡萄糖处理之间的平衡。
Diabetes. 2016 Jan;65(1):53-61. doi: 10.2337/db15-0770.
6
MicroRNAs and type 2 diabetes/obesity.微小 RNA 与 2 型糖尿病/肥胖症。
J Genet Genomics. 2012 Jan;39(1):11-8. doi: 10.1016/j.jgg.2011.11.007. Epub 2011 Dec 29.
7
Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice.肥胖症和遗传学调节糖尿病小鼠胰岛、肝脏和脂肪组织中的 microRNAs。
Mamm Genome. 2009 Aug;20(8):476-85. doi: 10.1007/s00335-009-9217-2.
8
The involvement of microRNAs in Type 2 diabetes.微小 RNA 与 2 型糖尿病的关系。
Biochem Soc Trans. 2010 Dec;38(6):1565-70. doi: 10.1042/BST0381565.
9
Dysregulation of microRNA-125a contributes to obesity-associated insulin resistance and dysregulates lipid metabolism in mice.miR-125a 的失调导致肥胖相关的胰岛素抵抗，并调节小鼠的脂质代谢。
Biochim Biophys Acta Mol Cell Biol Lipids. 2020 May;1865(5):158640. doi: 10.1016/j.bbalip.2020.158640. Epub 2020 Jan 25.
10
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism.MAFG- lncRNA 轴将全身营养物质丰度与肝脏葡萄糖代谢联系起来。
Nat Commun. 2020 Jan 31;11(1):644. doi: 10.1038/s41467-020-14323-y.

引用本文的文献

1
The role of miR-143/miR-145 in the development, diagnosis, and treatment of diabetes.miR-143/miR-145在糖尿病发生、诊断及治疗中的作用
J Diabetes Metab Disord. 2023 Oct 11;23(1):39-47. doi: 10.1007/s40200-023-01317-y. eCollection 2024 Jun.
2
Developmental programming: Adipose depot-specific regulation of non-coding RNAs and their relation to coding RNA expression in prenatal testosterone and prenatal bisphenol-A -treated female sheep.发育编程：脂肪组织特异性调节非编码 RNA 及其与产前睾酮和产前双酚 A 处理雌性绵羊编码 RNA 表达的关系。
Mol Cell Endocrinol. 2023 Mar 15;564:111868. doi: 10.1016/j.mce.2023.111868. Epub 2023 Jan 26.
3
Cardiac Metabolism and MiRNA Interference.心脏代谢与 miRNA 干扰
Int J Mol Sci. 2022 Dec 20;24(1):50. doi: 10.3390/ijms24010050.
4
A Review of miRNAs as Biomarkers and Effect of Dietary Modulation in Obesity Associated Cognitive Decline and Neurodegenerative Disorders.作为生物标志物的微小RNA以及饮食调节对肥胖相关认知衰退和神经退行性疾病的影响综述
Front Mol Neurosci. 2021 Oct 7;14:756499. doi: 10.3389/fnmol.2021.756499. eCollection 2021.
5
Body fat composition and miR-378 expression profiling in patients with type 1 diabetes.1型糖尿病患者的体脂成分与miR-378表达谱分析
Ann Pediatr Endocrinol Metab. 2020 Jun;25(2):118-125. doi: 10.6065/apem.1938088.044. Epub 2020 Jun 30.
6
MiRNAs as Novel Adipokines: Obesity-Related Circulating MiRNAs Influence Chemosensitivity in Cancer Patients.微小RNA作为新型脂肪因子：与肥胖相关的循环微小RNA影响癌症患者的化疗敏感性。
Noncoding RNA. 2020 Jan 23;6(1):5. doi: 10.3390/ncrna6010005.
7
Macrophage-Derived microRNA-155 Increases in Obesity and Influences Adipocyte Metabolism by Targeting Peroxisome Proliferator-Activated Receptor Gamma.肥胖症中巨噬细胞衍生的 microRNA-155 增加，并通过靶向过氧化物酶体增殖物激活受体 γ 影响脂肪细胞代谢。
Obesity (Silver Spring). 2019 Nov;27(11):1856-1864. doi: 10.1002/oby.22616. Epub 2019 Sep 18.
8
Differential expression of miRNAs related to angiogenesis and adipogenesis in subcutaneous fat of obese and nonobese women.肥胖和非肥胖女性皮下脂肪中与血管生成和脂肪生成相关的微小RNA的差异表达
Mol Biol Rep. 2019 Feb;46(1):965-973. doi: 10.1007/s11033-018-4553-5. Epub 2018 Dec 18.
9
Exercise Training-Induced Changes in MicroRNAs: Beneficial Regulatory Effects in Hypertension, Type 2 Diabetes, and Obesity.运动训练引起的 microRNAs 变化：在高血压、2 型糖尿病和肥胖中的有益调节作用。
Int J Mol Sci. 2018 Nov 15;19(11):3608. doi: 10.3390/ijms19113608.
10
The miRNAome of the postpartum dairy cow liver in negative energy balance.能量负平衡状态下产后奶牛肝脏的微小RNA组
BMC Genomics. 2014 Apr 12;15:279. doi: 10.1186/1471-2164-15-279.

本文引用的文献

1
Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism.肥胖诱导的 miRNA-143 过表达抑制胰岛素刺激的 AKT 激活并损害葡萄糖代谢。
Nat Cell Biol. 2011 Apr;13(4):434-46. doi: 10.1038/ncb2211. Epub 2011 Mar 27.
2
MicroRNAs and cardiovascular diseases.微小 RNA 与心血管疾病。
FEBS J. 2011 May;278(10):1619-33. doi: 10.1111/j.1742-4658.2011.08090.x. Epub 2011 Mar 30.
3
MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo.Srebp2 内含子编码的 microRNA-33 可在体内调节 HDL。
Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17321-6. doi: 10.1073/pnas.1008499107. Epub 2010 Sep 20.
4
miR-375 maintains normal pancreatic alpha- and beta-cell mass.微小RNA-375维持胰腺α细胞和β细胞的正常数量。
Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5813-8. doi: 10.1073/pnas.0810550106. Epub 2009 Mar 16.
5
A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence.对编码区域中保守序列的搜索显示，let-7微小RNA在其编码序列内靶向Dicer。
Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):14879-84. doi: 10.1073/pnas.0803230105. Epub 2008 Sep 23.
6
MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation.针对Nanog、Oct4和Sox2编码区域的微小RNA可调节胚胎干细胞分化。
Nature. 2008 Oct 23;455(7216):1124-8. doi: 10.1038/nature07299. Epub 2008 Sep 17.
7
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.一项针对芬兰人2型糖尿病的全基因组关联研究发现了多个易感变异体。
Science. 2007 Jun 1;316(5829):1341-5. doi: 10.1126/science.1142382. Epub 2007 Apr 26.
8
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.全基因组关联分析确定2型糖尿病和甘油三酯水平的基因座。
Science. 2007 Jun 1;316(5829):1331-6. doi: 10.1126/science.1142358. Epub 2007 Apr 26.
9
A genome-wide association study identifies novel risk loci for type 2 diabetes.一项全基因组关联研究确定了2型糖尿病的新风险位点。
Nature. 2007 Feb 22;445(7130):881-5. doi: 10.1038/nature05616. Epub 2007 Feb 11.
10
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes.转录因子7样蛋白2（TCF7L2）基因变体赋予2型糖尿病风险。
Nat Genet. 2006 Mar;38(3):320-3. doi: 10.1038/ng1732. Epub 2006 Jan 15.

MicroRNA links obesity and impaired glucose metabolism.

作者信息

Ono Koh

机构信息

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, 54 Shogoin-kawahara-cho, Sakyo-ku, Kyoto, 606-8397, Japan.

出版信息

Cell Res. 2011 Jun;21(6):864-6. doi: 10.1038/cr.2011.78. Epub 2011 May 10.

DOI:10.1038/cr.2011.78
PMID:21556034
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3203709/
Abstract
摘要