Department of Occupational and Environmental Dermatology, Skåne University Hospital, Lund University, SE-205 02 Malmö, Sweden.
Contact Dermatitis. 2011 Jul;65(1):34-7. doi: 10.1111/j.1600-0536.2011.01921.x. Epub 2011 May 19.
Contact allergy to phenol-formaldehyde resins (PFRs) based on phenol and formaldehyde is not detected by a p-tertiary-butylphenol-formaldehyde resin (PTBP-FR) included in most baseline patch test series.
To investigate the rate of contact allergy to PFR-2 (a mixture of monomers and dimers from a resol resin based on phenol and formaldehyde) in a Swedish population, and to investigate associated simultaneous allergic reactions.
Five centres representing the Swedish Contact Dermatitis Research Group included PFR-2 in their patch test baseline series for a period of 1.5 years.
Of 2504 patients tested, 27 (1.1%) reacted to PFR-2. Of those 27 individuals, 2 had a positive reaction to formaldehyde and 2 to PTBP-FR. Simultaneous allergic reactions were noted to colophonium in 6, to Myroxylon pereirae in 14, and to fragrance mix I in 15.
The contact allergy frequency in the tested population (1.1%) merits its inclusion in the Swedish baseline series and possibly also in other baseline series. Simultaneous allergic reactions were noted to colophonium, M. pereirae, and fragrance mix I.
基于苯酚和甲醛的酚醛树脂（PFR）引起的接触过敏不能通过大多数斑贴试验系列中包含的对叔丁基苯酚-甲醛树脂（PTBP-FR）来检测。
研究在瑞典人群中对 PFR-2（基于苯酚和甲醛的树脂的单体和二聚体混合物）的接触过敏率，并研究其相关的同时过敏反应。
代表瑞典接触性皮炎研究组的五个中心在他们的斑贴试验基础系列中加入了 PFR-2，为期 1.5 年。
在 2504 名接受测试的患者中，有 27 人（1.1%）对 PFR-2 有反应。在这 27 个人中，有 2 人对甲醛和 2 人对 PTBP-FR 有阳性反应。同时还注意到对松香的过敏反应有 6 例，对秘鲁香脂的过敏反应有 14 例，对香料混合物 I 的过敏反应有 15 例。
在测试人群中（1.1%）接触过敏的频率表明其有必要纳入瑞典基础系列，也可能纳入其他基础系列。同时还注意到对松香、秘鲁香脂和香料混合物 I 的过敏反应。
