Mountain Research Centre (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, Apartado 1172, 5301-855 Bragança, Portugal.
Molecules. 2011 May 25;16(6):4328-38. doi: 10.3390/molecules16064328.
The use of natural products isolated from mushrooms, included inedible species, against infection, cancer diseases and other oxidative-stress related diseases is one of the cornerstones of modern medicine. In the present work, the antioxidant molecule profiles of inedible mushroom species were evaluated and compared with those of edible species. The order of antioxidant abundance found in inedible wild mushrooms was: phenolics > flavonoids > ascorbic acid > tocopherols > carotenoids, similar to that of edible species. Furthermore the same energetic biomolecules were found including the disaccharide trehalose, the monosaccharide alcohol derivative mannitol and the fatty acids palmitic, oleic and linoleic acids. Fomitopsis pinicola revealed a very high phenolics concentration (388 mg GAE/g extract) and powerful antioxidant properties, mainly reducing power (EC₅₀) value 60 μg/mL similar to the standard Trolox®). It could find applications in the prevention of free radical-related diseases as a source of bioactive compounds.
利用从蘑菇中分离出的天然产物，包括不可食用的物种，来对抗感染、癌症疾病和其他与氧化应激相关的疾病，是现代医学的基石之一。在本工作中，评估了不可食用蘑菇物种的抗氧化分子谱，并将其与可食用物种进行了比较。不可食用野生蘑菇中抗氧化剂丰度的顺序为：酚类>类黄酮>抗坏血酸>生育酚>类胡萝卜素，与可食用物种相似。此外，还发现了相同的高能生物分子，包括二糖海藻糖、单糖醇衍生物甘露醇和脂肪酸棕榈酸、油酸和亚油酸。栓菌显示出非常高的酚类浓度（388 mg GAE/g 提取物）和强大的抗氧化特性，主要是还原能力（EC₅₀）值为 60 μg/mL，与标准 Trolox®相似。它可以作为生物活性化合物的来源，用于预防自由基相关疾病。
