细胞凋亡研究新进展：在微流控芯片上分析程序性细胞死亡。
Apoptosis goes on a chip: advances in the microfluidic analysis of programmed cell death.
机构信息
The BioMEMS Research Group, Department of Chemistry, University of Auckland, Auckland, New Zealand.
出版信息
Anal Chem. 2011 Sep 1;83(17):6439-46. doi: 10.1021/ac200588g. Epub 2011 Jun 16.
Abstract
Recent years have brought enormous progress in cell-based lab-on-a-chip technologies, allowing dynamic studies of cell death with an unprecedented accuracy. As interest in the microfabricated technologies for cell-based bioassays is rapidly gaining momentum, we highlight the most promising technologies that provide a new outlook for the rapid assessment of programmed and accidental cell death and are applicable in drug discovery, high-content drug screening, and personalized clinical diagnostics.
摘要
近年来，基于细胞的芯片实验室技术取得了巨大的进展，使细胞死亡的动态研究达到了前所未有的精确程度。随着对基于细胞的生物测定微加工技术的兴趣迅速增强，我们重点介绍了最有前途的技术，这些技术为快速评估程序性和意外细胞死亡提供了新的视角，并且适用于药物发现、高通量药物筛选和个性化临床诊断。
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