Gervais C, Suh M
Department of Medicine, University of Montreal, Quebec, Canada.
Mol Cell Biol. 1990 Aug;10(8):4412-4. doi: 10.1128/mcb.10.8.4412-4414.1990.
A nearly full-length cDNA very similar to murine serum amyloid A protein was cloned from herpes simplex virus type 2-transformed hamster cells. The expression of mRNA was constitutive in these cells and could be superinduced by conditioned medium. Higher rates of nuclear runoff transcription in transformed and induced cells indicated some regulation at the transcriptional level.
从单纯疱疹病毒2型转化的仓鼠细胞中克隆出了一个与小鼠血清淀粉样蛋白A非常相似的几乎全长的cDNA。这些细胞中mRNA的表达是组成型的,并且可以被条件培养基超诱导。转化细胞和诱导细胞中更高的核转录速率表明在转录水平存在一些调控。