Medical Research Council Epidemiology Unit, Cambridge, United Kingdom.
PLoS One. 2011;6(5):e20058. doi: 10.1371/journal.pone.0020058. Epub 2011 May 25.
Although television viewing time is detrimentally associated with intermediate cardiovascular risk factors, the relationship with incident total (i.e. combined fatal and non-fatal) cardiovascular disease (CVD), non-fatal CVD and coronary heart disease is largely unknown. This study examined whether television viewing time is associated with these three outcomes, independently of physical activity energy expenditure and other confounding variables.
METHODOLOGY/PRINCIPAL FINDINGS: A population-based cohort of 12,608 men and women (aged 61.4±9.0), free from stroke, myocardial infarction and cancer at baseline in 1998-2000 were followed up until 2007 (6.9±1.9 years). Participants self-reported education, smoking, alcohol use, antihypertensive, lipid lowering and antidepressant medication, disease history, total energy intake, sleep duration, physical activity and television viewing. BMI, waist circumference, blood pressure, triglycerides, HDL cholesterol and glycated haemoglobin (HbA(1c)) were measured by standardized procedures; a clustered metabolic risk score was constructed. Every one hour/day increase in television viewing was associated with an increased hazard for total (HR = 1.06, 95%CI = 1.03-1.08; 2,620 cases), non-fatal CVD (HR = 1.06, 95%CI = 1.03-1.09; 2,134 cases), and coronary heart disease (HR = 1.08, 95%CI = 1.03-1.13; 940 cases), independent of gender, age, education, smoking, alcohol, medication, diabetes status, CVD family history, sleep duration and physical activity energy expenditure. Energy intake, BMI, waist circumference, blood pressure, triglycerides, HDL cholesterol, HbA(1c) and the clustered metabolic risk score only partially mediated these associations.
These results indicate that the most prevalent leisure time (sedentary) behaviour, television viewing, independently contributes to increased CVD risk. Recommendations on reducing television viewing time should be considered.
尽管看电视时间与心血管疾病的中间风险因素呈负相关，但与心血管疾病的发生（即包括致命和非致命）、非致命性心血管疾病和冠心病的关系在很大程度上还不清楚。本研究旨在检验看电视时间与这三种结果的关系，而不考虑体力活动的能量消耗和其他混杂因素。
方法/主要发现：本研究基于人群的队列研究包括 12608 名男性和女性（年龄 61.4±9.0），在 1998-2000 年基线时无中风、心肌梗死和癌症，随访至 2007 年（6.9±1.9 年）。参与者报告了教育、吸烟、饮酒、降压、降脂和抗抑郁药物、疾病史、总能量摄入、睡眠时间、体力活动和看电视时间。BMI、腰围、血压、甘油三酯、HDL 胆固醇和糖化血红蛋白（HbA1c）采用标准化程序测量；构建了一个聚类代谢风险评分。每天看电视时间每增加 1 小时，总发病风险（HR=1.06，95%CI=1.03-1.08；2620 例）、非致命性心血管疾病（HR=1.06，95%CI=1.03-1.09；2134 例）和冠心病（HR=1.08，95%CI=1.03-1.13；940 例）的风险均会增加，且独立于性别、年龄、教育、吸烟、饮酒、药物治疗、糖尿病状态、心血管疾病家族史、睡眠时间和体力活动能量消耗。能量摄入、BMI、腰围、血压、甘油三酯、HDL 胆固醇、HbA1c 和聚类代谢风险评分仅部分介导了这些关联。
这些结果表明，最常见的休闲时间（久坐）行为——看电视，独立地增加了 CVD 风险。应该考虑减少看电视时间的建议。
