Mahajan Vineet, Whig Jagdeep, Kashyap Anil, Gupta Sushil
Department of Pulmonary and Critical Care, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
Lung India. 2011 Jan;28(1):52-5. doi: 10.4103/0970-2113.76302.
Diffuse alveolar hemorrhage is a life-threatening though rare manifestation of Wegener's granulomatosis (WG). An active diagnostic workup, intensive observation, and aggressive immunosuppressive treatment are cornerstones of the management. The treatment modalities available for such complications are pulse cyclophosphamide therapy with steroids. We report here a case of WG with diffuse alveolar hemorrhage as the first manifestation of the disease in life that responded to steroids and cyclophosphamide.
弥漫性肺泡出血是韦格纳肉芽肿(WG)一种虽罕见但危及生命的表现。积极的诊断检查、密切观察和积极的免疫抑制治疗是治疗的基石。针对此类并发症的可用治疗方式是联合类固醇进行环磷酰胺冲击治疗。我们在此报告一例以弥漫性肺泡出血为该病首发表现的WG病例,该病例对类固醇和环磷酰胺治疗有反应。