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帕金森病的视觉症状。

Visual symptoms in Parkinson's disease.

机构信息

Department of Vision Sciences, Aston University, Birmingham B4 7ET, UK.

出版信息

Parkinsons Dis. 2011;2011:908306. doi: 10.4061/2011/908306. Epub 2011 May 25.

Abstract

Parkinson's disease (PD) is a common disorder of middle-aged and elderly people in which degeneration of the extrapyramidal motor system causes significant movement problems. In some patients, however, there are additional disturbances in sensory systems including loss of the sense of smell and auditory and/or visual problems. This paper is a general overview of the visual problems likely to be encountered in PD. Changes in vision in PD may result from alterations in visual acuity, contrast sensitivity, colour discrimination, pupil reactivity, eye movements, motion perception, visual field sensitivity, and visual processing speeds. Slower visual processing speeds can also lead to a decline in visual perception especially for rapidly changing visual stimuli. In addition, there may be disturbances of visuospatial orientation, facial recognition problems, and chronic visual hallucinations. Some of the treatments used in PD may also have adverse ocular reactions. The pattern electroretinogram (PERG) is useful in evaluating retinal dopamine mechanisms and in monitoring dopamine therapies in PD. If visual problems are present, they can have an important effect on the quality of life of the patient, which can be improved by accurate diagnosis and where possible, correction of such defects.

摘要

帕金森病(PD)是一种常见的中老年疾病,其中锥体外系运动系统的退化导致严重的运动问题。然而,在一些患者中,还存在其他感觉系统的紊乱,包括嗅觉丧失以及听觉和/或视觉问题。本文概述了 PD 中可能遇到的视觉问题。PD 中的视力变化可能源于视力、对比敏感度、颜色辨别力、瞳孔反应性、眼球运动、运动知觉、视野敏感性和视觉处理速度的改变。较慢的视觉处理速度也会导致视觉感知下降,尤其是对于快速变化的视觉刺激。此外,可能存在视空间定向障碍、面部识别问题和慢性视觉幻觉。PD 中使用的一些治疗方法也可能对眼部产生不良反应。图形视网膜电图(PERG)有助于评估视网膜多巴胺机制,并监测 PD 中的多巴胺治疗。如果存在视觉问题,它们会对患者的生活质量产生重要影响,如果能准确诊断并尽可能纠正这些缺陷,就可以改善生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acf5/3109513/59acbaa1e2eb/PD2011-908306.001.jpg

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