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与药物相关的住院情况的发生率及性质:在一家三级医疗保健医院进行的为期6个月的观察性研究。

The incidence and nature of drug-related hospital admission: A 6-month observational study in a tertiary health care hospital.

作者信息

Singh Harminder, Kumar Bithika Nel, Sinha Tiku, Dulhani Navin

机构信息

Department of Pharmacology, Govt. Medical College, Jagdalpur, Chhattisgarh, India.

出版信息

J Pharmacol Pharmacother. 2011 Jan;2(1):17-20. doi: 10.4103/0976-500X.77095.

Abstract

OBJECTIVE

To assess and evaluate the frequency, severity and classification of drug-related problems (DRP) resulting in hospitalization in an internal medicine department of a large tertiary care hospital and to identify any patient, prescriber, drug, and system factors associated with these events.

MATERIALS AND METHODS

A prospective and descriptive study carried out in Department of Medicine, Government Medical College, Jagdalpur. The DRP and relevant data were recorded on the personal record of every individual patient, filled during the course of treatment.

RESULT

A total of 3560 patient's records were analyzed. Among them118 admissions were due to DRP. The most common DRP noted was noncompliance in part of patient's i.e 55 (46.6%). Statistically significant correlations were found in the number of prescribed drugs and over the counter drugs (OTC) used by patients.

CONCLUSION

The DRP that attributed to hospital admission are mostly avoidable through proper patient education and strengthening the need of pharmacovigilance with little more vigilance in patient care.

摘要

目的

评估和评价一家大型三级医疗医院内科导致住院的药物相关问题(DRP)的发生频率、严重程度和分类,并确定与这些事件相关的任何患者、开处方者、药物和系统因素。

材料与方法

在贾格德尔布尔政府医学院内科进行的一项前瞻性描述性研究。在治疗过程中,将DRP及相关数据记录在每位患者的个人记录中。

结果

共分析了3560份患者记录。其中118例住院是由于DRP。最常见的DRP是患者部分不依从,即55例(46.6%)。在患者使用的处方药和非处方药(OTC)数量上发现了具有统计学意义的相关性。

结论

通过适当的患者教育以及加强药物警戒需求,并在患者护理中多加注意,可避免大多数导致住院的DRP。

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Drug-related hospital admissions in a generic pharmaceutical system.仿制药体系中与药物相关的住院情况。
Clin Exp Pharmacol Physiol. 2007 May-Jun;34(5-6):494-8. doi: 10.1111/j.1440-1681.2007.04600.x.
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Nature and causes of clinically significant medication errors in a tertiary care hospital.
Am J Health Syst Pharm. 2004 Sep 15;61(18):1908-16. doi: 10.1093/ajhp/61.18.1908.
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Drug-related problem classification systems.药物相关问题分类系统
Ann Pharmacother. 2004 May;38(5):859-67. doi: 10.1345/aph.1D182. Epub 2004 Mar 30.

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