Department of Medical Protein Research, VIB, Ghent, Belgium.
J Proteome Res. 2011 Aug 5;10(8):3840-3. doi: 10.1021/pr2005154. Epub 2011 Jul 11.
The Thermo Proteome Discoverer program integrates both peptide identification and quantification into a single workflow for peptide-centric proteomics. Furthermore, its close integration with Thermo mass spectrometers has made it increasingly popular in the field. Here, we present a Java library to parse the msf files that constitute the output of Proteome Discoverer. The parser is also implemented as a graphical user interface allowing convenient access to the information found in the msf files, and in Rover, a program to analyze and validate quantitative proteomics information. All code, binaries, and documentation is freely available at http://thermo-msf-parser.googlecode.com.
Thermo Proteome Discoverer 程序将肽鉴定和定量整合到一个以肽为中心的蛋白质组学工作流程中。此外，它与 Thermo 质谱仪的紧密集成使其在该领域越来越受欢迎。在这里，我们提供了一个 Java 库来解析构成 Proteome Discoverer 输出的 msf 文件。该解析器也被实现为一个图形用户界面，允许方便地访问 msf 文件中的信息，以及 Rover 程序来分析和验证定量蛋白质组学信息。所有代码、二进制文件和文档都可以在 http://thermo-msf-parser.googlecode.com 上免费获得。
