Moss Rehabilitation Research Institute, Elkins Park, PA 191027, USA.
Cogn Neuropsychol. 2010 Sep;27(6):477-94. doi: 10.1080/02643294.2011.574111. Epub 2011 Jun 30.
Case series methodology involves the systematic assessment of a sample of related patients, with the goal of understanding how and why they differ from one another. This method has become increasingly important in cognitive neuropsychology, which has long been identified with single-subject research. We review case series studies dealing with impaired semantic memory, reading, and language production and draw attention to the affinity of this methodology for testing theories that are expressed as computational models and for addressing questions about neuroanatomy. It is concluded that case series methods usefully complement single-subject techniques.
病例系列研究方法涉及对一组相关患者进行系统评估,目的是了解他们彼此之间的差异及其产生的原因。这种方法在认知神经心理学领域变得越来越重要,认知神经心理学长期以来一直与单一被试研究相关联。我们对涉及语义记忆、阅读和语言产生障碍的病例系列研究进行了回顾,并提请注意这种方法在测试以计算模型表达的理论以及解决神经解剖问题方面的适用性。结论认为,病例系列研究方法对补充单一被试技术是有用的。