Laboratoire d'Analyses, Traitement et Valorisation des Polluants de l'Environnement et des Produits, Université de Monastir, Tunisie.
BMC Microbiol. 2011 Jun 29;11:155. doi: 10.1186/1471-2180-11-155.
Enterococci are increasingly associated with opportunistic infections in Humans but the role of the oral cavity as a reservoir for this species is unclear. This study aimed to explore the carriage rate of Enterococci in the oral cavity of Tunisian children and their antimicrobial susceptibility to a broad range of antibiotics together with their adherence ability to abiotic and biotic surfaces.
In this study, 17 E. faecalis (27.5%) and 4 E. faecium (6.5%) were detected. The identified strains showed resistance to commonly used antibiotics. Among the 17 isolated E. faecalis, 12 strains (71%) were slime producers and 5 strains were non-producers. Among the 4 E. faecium, 2 strains were slime producers. All the tested strains were able to adhere to at least one of the two tested cell lines. Our result showed that 11 E. faecalis and 2 E. faecium strains adhered strongly to Hep-2 as well as to A549 cells.
Drugs resistance and strong biofilm production abilities together with a high phenotypic adhesion to host cells are important equipment in E. faecalis and E. faecium which lead to their oral cavity colonization and focal infections.
肠球菌越来越多地与人类的机会性感染有关，但口腔作为该物种的储库的作用尚不清楚。本研究旨在探索突尼斯儿童口腔中肠球菌的携带率及其对广泛抗生素的药敏性，以及它们对非生物和生物表面的黏附能力。
在这项研究中，检测到 17 株粪肠球菌（27.5%）和 4 株屎肠球菌（6.5%）。鉴定出的菌株对常用抗生素表现出耐药性。在分离出的 17 株粪肠球菌中，有 12 株（71%）为黏液产生菌，5 株为非产黏液菌。4 株屎肠球菌中有 2 株为黏液产生菌。所有测试的菌株都能够至少黏附到两种测试细胞系中的一种。我们的结果表明，11 株粪肠球菌和 2 株屎肠球菌菌株强烈黏附 Hep-2 和 A549 细胞。
耐药性和强生物膜生成能力以及对宿主细胞的高表型黏附是粪肠球菌和屎肠球菌的重要特征，导致它们在口腔定植和局部感染。
