Itakura S, Aoki K, Sawada H, Shinagawa M
Department of Veterinary Public Health, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan.
J Clin Microbiol. 1990 Oct;28(10):2365-9. doi: 10.1128/jcm.28.10.2365-2369.1990.
A total of 49 adenovirus type 3 (Ad3) strains from patients with epidemic keratoconjunctivitis at an eye clinic in Sapporo, Japan, from 1983 to 1986 were classified into either genome type Ad3f (26 strains) or Ad3g (23 strains). By the use of Hinf1 and TaqI restriction endonucleases, they were classified into 11 and 3 subgenome types, respectively. During this observation period, two epidemics of Ad3 infection relating to epidemic keratoconjunctivitis occurred. The prevalent Ad3g strains isolated during the epidemic in 1983 belonged to a single subgenome type. However, in the course of the Ad3f epidemic in 1986, alteration of one subgenome type of the prevalent strain to a different subgenome type which was presumed to be a derivative of the former was observed. In the years in which only a few Ad3 strains were isolated, such Ad3f strains were classified into different subgenome types. However, all Ad3g strains except two belonged to the same subgenome type.
1983年至1986年期间，从日本札幌一家眼科诊所的流行性角结膜炎患者中总共分离出49株3型腺病毒（Ad3），这些病毒被分为基因组类型Ad3f（26株）或Ad3g（23株）。利用Hinf1和TaqI限制性内切酶，它们分别被分为11种和3种亚基因组类型。在该观察期内，发生了两起与流行性角结膜炎相关的Ad3感染疫情。1983年疫情期间分离出的流行Ad3g毒株属于单一亚基因组类型。然而，在1986年Ad3f疫情期间，观察到流行毒株的一种亚基因组类型转变为另一种被认为是前者衍生物的不同亚基因组类型。在分离出的Ad3毒株较少的年份，此类Ad3f毒株被分为不同的亚基因组类型。然而，除两株外，所有Ad3g毒株都属于同一亚基因组类型。
