Kango Prasad G, Deshmukh Rs
Department of Oral and Maxillofacial Pathology and Microbiology, Bharati Vidyapeeth Dental College and Hospital, Pune, India.
J Oral Maxillofac Pathol. 2011 Jan;15(1):6-13. doi: 10.4103/0973-029X.80031.
Research in oral and maxillofacial pathology has unlimited potential. We use every technology available to us for better and faster reliable diagnosis. But in most institutions, private laboratories and multispecialty hospitals, tissue processing takes considerable time, and therefore delays the diagnosis, which is required in urgent cases. We, in this institution, conducted a study to hasten the processing by using a simple kitchen microwave.
To analyze tissue sections processed by microwave as compared to the gold standard of conventional processing.
Studies published from 1970 till 2008, used body tissues such as brain, liver, kidney, heart, and lungs, for microwave processing. Oral tissues were not processed in microwave till now, except one study by Dr Shivaparthasundaram et al., in 2008. This is the second such study that used a sample size of 50 cases.
A kitchen microwave was used for irradiation of the tissues. Conventional processing was carried out as per departmental protocol. A total of 50 microwave-coded slides were mixed with 50 conventional slides. All 100 slides were evaluated by four different pathologists.
The result was subjected to statistical analysis using Chi-square test.
It was found that to make a diagnosis, microwave-processed tissue were at par with the conventional technique. Thus, it is time to move on from conventional processing to microwave processing to yield faster and reliable results.
口腔颌面病理学研究具有无限潜力。我们利用一切可用技术以实现更准确、快速的可靠诊断。但在大多数机构、私立实验室和多专科医院中,组织处理耗时颇长,从而延误了诊断,而在紧急情况下诊断是必需的。我们所在的机构开展了一项研究,通过使用简单的厨房微波炉来加快处理速度。
将经微波处理的组织切片与传统处理的金标准进行比较分析。
1970年至2008年发表的研究使用脑、肝、肾、心和肺等身体组织进行微波处理。到目前为止,除了2008年Shivaparthasundaram博士等人的一项研究外,口腔组织尚未进行微波处理。这是第二项此类研究,样本量为50例。
使用厨房微波炉对组织进行照射。按照部门规程进行传统处理。将总共50张经微波编码的玻片与50张传统玻片混合。所有100张玻片由四位不同的病理学家进行评估。
结果采用卡方检验进行统计分析。
发现为做出诊断,经微波处理的组织与传统技术相当。因此,是时候从传统处理转向微波处理以获得更快且可靠的结果了。