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Chlamydia trachomatis strains and virulence: rethinking links to infection prevalence and disease severity.沙眼衣原体株系与毒力:重新思考其与感染流行率和疾病严重程度的关系。
J Infect Dis. 2010 Jun 15;201 Suppl 2(Suppl 2):S126-33. doi: 10.1086/652398.
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Lymphogranuloma venereum in Europe, 2003-2008.欧洲 2003-2008 年的性病性淋巴肉芽肿。
Euro Surveill. 2009 Dec 3;14(48):19428. doi: 10.2807/ese.14.48.19428-en.
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Evolutionary dynamics of ompA, the gene encoding the Chlamydia trachomatis key antigen.沙眼衣原体关键抗原编码基因ompA的进化动力学
J Bacteriol. 2009 Dec;191(23):7182-92. doi: 10.1128/JB.00895-09. Epub 2009 Sep 25.
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Emergence and spread of Chlamydia trachomatis variant, Sweden.沙眼衣原体变种在瑞典的出现与传播
Emerg Infect Dis. 2008 Sep;14(9):1462-5. doi: 10.3201/eid1409.080153.
5
Chlamydia trachomatis OmpA genotyping as a tool for studying the natural history of genital chlamydial infection.沙眼衣原体OmpA基因分型作为研究生殖道衣原体感染自然史的工具。
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Highly discriminative genotyping of Chlamydia trachomatis using omp1 and a set of variable number tandem repeats.利用omp1和一组可变数目串联重复序列对沙眼衣原体进行高分辨基因分型
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Chlamydia trachomatis reinfection rates among female adolescents seeking rescreening in school-based health centers.在校立健康中心寻求再次筛查的女性青少年中沙眼衣原体再感染率。
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TaqMan assay for Swedish Chlamydia trachomatis variant.用于瑞典沙眼衣原体变种的TaqMan检测法。
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Results of a Europe-wide investigation to assess the presence of a new variant of Chlamydia trachomatis.一项全欧洲范围的调查结果,该调查旨在评估沙眼衣原体新变种的存在情况。
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Experiences with the new genetic variant of Chlamydia trachomatis in Orebro county, Sweden - proportion, characteristics and effective diagnostic solution in an emergent situation.瑞典厄勒布鲁县沙眼衣原体新基因变体的情况——紧急情况下的比例、特征及有效诊断方法
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芬兰泌尿生殖系统沙眼衣原体菌株中的沙眼衣原体基因型及瑞典新变体

Chlamydia trachomatis genotypes and the Swedish new variant among urogenital Chlamydia trachomatis strains in Finland.

作者信息

Niemi Suvi, Hiltunen-Back Eija, Puolakkainen Mirja

机构信息

Haartman Institute, Department of Virology, University of Helsinki, 00014 University of Helsinki, Finland.

出版信息

Infect Dis Obstet Gynecol. 2011;2011:481890. doi: 10.1155/2011/481890. Epub 2011 May 18.

DOI:10.1155/2011/481890
PMID:21747641
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3124027/
Abstract

Our aims were to genotype Chlamydia trachomatis strains present in urogenital samples and to investigate the occurrence of the Swedish new variant of C. trachomatis in Finland. We genotyped 160 C. trachomatis positive samples with ompA real-time PCR and analyzed 495 samples for the new variant. The three most prevalent genotypes were E (40%), F (28%), and G (13%). Only two specimens containing bacteria with the variant plasmid were detected. It seems that in Finland the percentage of infections due to genotypes F and G has slightly increased during the last 20 years. Genotypes E and G appear to be more common, and genotypes J/Ja and I/Ia appear to be less common in Europe than in the USA. Although the genotype E was the most common genotype among C. trachomatis strains, the new variant was rarely found in Finland.

摘要

我们的目的是对泌尿生殖系统样本中存在的沙眼衣原体菌株进行基因分型,并调查芬兰沙眼衣原体瑞典新变种的出现情况。我们使用ompA实时聚合酶链反应对160份沙眼衣原体阳性样本进行基因分型,并对495份样本进行新变种分析。三种最常见的基因型是E(40%)、F(28%)和G(13%)。仅检测到两份含有携带变异质粒细菌的标本。在芬兰,过去20年中由基因型F和G引起的感染百分比似乎略有增加。在欧洲,基因型E和G似乎更为常见,而基因型J/Ja和I/Ia似乎比在美国少见。虽然基因型E是沙眼衣原体菌株中最常见的基因型,但在芬兰很少发现新变种。