SeaWorld, San Diego, California 92109, USA.
Emerg Infect Dis. 2011 Aug;17(8):1531-3. doi: 10.3201/eid1708.101979.
In 2007, nonsuppurative encephalitis was identified in a killer whale at a Texas, USA, marine park. Panviral DNA microarray of brain tissue suggested West Nile virus (WNV); WNV was confirmed by reverse transcription PCR and sequencing. Immunohistochemistry demonstrated WNV antigen within neurons. WNV should be considered in cases of encephalitis in cetaceans.
2007 年,在美国德克萨斯州的一个海洋公园中,一头虎鲸被诊断患有非化脓性脑炎。脑组织的泛病毒 DNA 微阵列检测提示存在西尼罗河病毒(WNV);通过反转录 PCR 和测序进一步证实了 WNV 的存在。免疫组织化学显示神经元内存在 WNV 抗原。WNV 应被视为鲸类动物脑炎的病因之一。