Department of Clinical Microbiology, Hospital Clinic, CRESIB/IDIBAPS, School of Medicine, University of Barcelona, Barcelona, Spain.
Antimicrob Agents Chemother. 2011 Nov;55(11):5396-8. doi: 10.1128/AAC.00679-11. Epub 2011 Aug 8.
New Delhi metallo-β-lactamase (NDM-1) was initially identified in various Enterobacteriaceae and recently in Acinetobacter baumannii. This study described the clonal dissemination of an NDM-2-producing A. baumannii isolate in an Israeli rehabilitation ward and the genetic surroundings of the gene. The bla(NDM-2) gene was surrounded by the ble and trpF genes downstream and two copies of the ISAba125 on both sides. These are the first NDM-producing A. baumannii strains in Israel from patients with no previous travel or hospitalization on the Indian subcontinent.
新德里金属β-内酰胺酶（NDM-1）最初在各种肠杆菌科中被发现，最近也在鲍曼不动杆菌中被发现。本研究描述了在以色列一家康复病房中，一株产 NDM-2 的鲍曼不动杆菌的克隆传播情况，以及该基因的遗传环境。bla（NDM-2）基因下游被ble 和 trpF 基因包围，两侧各有两个 ISAba125 拷贝。这些是来自印度次大陆无既往旅行或住院史的患者的以色列首批产 NDM 的鲍曼不动杆菌菌株。
