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手握力是食管癌切除重建术后一个简单有效的预后预测指标:一项前瞻性研究。

Hand-grip strength is a simple and effective outcome predictor in esophageal cancer following esophagectomy with reconstruction: a prospective study.

作者信息

Chen Chih-Hao, Huang Yi-Zhen, Hung Tzu-Ti

机构信息

Department of Thoracic Surgery, Mackay Memorial Hospital, Taipei City, Taiwan.

出版信息

J Cardiothorac Surg. 2011 Aug 15;6:98. doi: 10.1186/1749-8090-6-98.

DOI:10.1186/1749-8090-6-98
PMID:21843340
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3170319/
Abstract

BACKGROUND

Surgery for esophageal cancer usually carries considerable complication and mortality rate. Adequate preoperative evaluation is mandatory to decrease complication rate. Hand-grip strength is a useful measure to assess the extent of aging, nutrition and patient's overall condition. Because preoperative nutrition state and physiologic aging process play important roles in postoperative recovery, we would like to know if hand-grip strength is an adequate tool for such evaluation.

MATERIAL AND METHODS

From January 1st, 2007 to December 31, 2008, there was 68 cases underwent esophagectomy with reconstruction due to esophageal cancer in our hospital. After excluding 7 patients of incomplete data and loss of follow-up, there were 61 patients included in the study.

RESULTS

There were 54 men and 7 women. The mean age is 60.7. Most of patients had squamous cell carcinoma. Patient with weak hand-grip strength prior to operation had exceedingly high rates of complication and mortality within 6 months after operation. Compared to other risk factors, low grip strength has highest relative risks for both mortality and morbidity.

CONCLUSION

Because test for hand-grip strength is cheap, not time-consuming and has high predictive value, it may be included in routine preoperative evaluation.

摘要

背景

食管癌手术通常伴随着较高的并发症和死亡率。进行充分的术前评估对于降低并发症发生率至关重要。握力是评估衰老程度、营养状况和患者整体状况的一项有用指标。由于术前营养状态和生理衰老过程对术后恢复起着重要作用,我们想了解握力是否是进行此类评估的合适工具。

材料与方法

2007年1月1日至2008年12月31日,我院有68例因食管癌接受食管切除术并重建的患者。排除7例数据不完整和失访的患者后,共有61例患者纳入本研究。

结果

男性54例,女性7例。平均年龄为60.7岁。大多数患者为鳞状细胞癌。术前握力较弱的患者术后6个月内并发症和死亡率极高。与其他危险因素相比,低握力对死亡率和发病率的相对风险最高。

结论

由于握力测试价格便宜、不耗时且具有较高的预测价值,它可能应纳入常规术前评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1710/3170319/b5f964a24c98/1749-8090-6-98-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1710/3170319/ed31b2d2488e/1749-8090-6-98-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1710/3170319/db9f7cb58012/1749-8090-6-98-2.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1710/3170319/56ee287a6f0b/1749-8090-6-98-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1710/3170319/adc10702903a/1749-8090-6-98-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1710/3170319/b5f964a24c98/1749-8090-6-98-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1710/3170319/ed31b2d2488e/1749-8090-6-98-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1710/3170319/db9f7cb58012/1749-8090-6-98-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1710/3170319/4b21c1e8b4fe/1749-8090-6-98-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1710/3170319/56ee287a6f0b/1749-8090-6-98-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1710/3170319/adc10702903a/1749-8090-6-98-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1710/3170319/b5f964a24c98/1749-8090-6-98-6.jpg

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