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电刺激脑疗法治疗伴有重性抑郁障碍的广泛性焦虑障碍:一项试点研究。

Radioelectric brain stimulation in the treatment of generalized anxiety disorder with comorbid major depression in a psychiatric hospital: a pilot study.

机构信息

Healthcare enterprise Hospital Trust S Croce and Carle Complex Structure of Psychiatry, Cuneo, Italy;

出版信息

Neuropsychiatr Dis Treat. 2011;7:449-55. doi: 10.2147/NDT.S23420. Epub 2011 Aug 4.

Abstract

BACKGROUND

Generalized anxiety disorder (GAD) is often presented with major depression (MD). GAD-MD can be a chronic and disabling condition, and patients suffering from this disorder often respond poorly to psychopharmacological treatment and experience side effects with medication. Therefore, there is a high demand for effective nonpharmacological therapy for GAD-MD patients. The current study explores the use of a radioelectric asymmetric conveyer (REAC) device in the treatment of GAD-MD.

METHODS

Participants were 24 patients diagnosed with GAD-MD being treated at a public psychiatric center. All patients were dissatisfied with their current pharmacological treatment. Patients were evaluated using the 21-item Hamilton Depression (HAM-D) rating scale and the Symptom Check List-90-Revised (SCL-90R) before and after REAC brain stimulation treatment cycles.

RESULTS

After REAC brain stimulation treatment, all patients experienced a significant reduction in anxiety and depression. These results were confirmed by physician examination, HAM-D scores, and SCL-90R total scores.

CONCLUSION

These results indicate a role for REAC brain stimulation in the management of psychiatric conditions, specifically, GAD-MD comorbidity. REAC treatments are synergistic to drug therapy and appear to be helpful in reducing the side effects of medication. Future studies should evaluate the long-term effects of REAC treatment.

摘要

背景

广泛性焦虑障碍(GAD)常伴有重度抑郁症(MD)。GAD-MD 可能是一种慢性和致残性疾病,患有这种疾病的患者对精神药理学治疗反应不佳,并因药物治疗而产生副作用。因此,对于 GAD-MD 患者来说,非常需要有效的非药物治疗。本研究探讨了使用无线电不对称传输器(REAC)设备治疗 GAD-MD。

方法

参与者为 24 名在公立精神科中心治疗的 GAD-MD 患者。所有患者对目前的药物治疗均不满意。在 REAC 脑刺激治疗周期前后,使用 21 项汉密尔顿抑郁量表(HAM-D)和症状清单-90 修订版(SCL-90R)对患者进行评估。

结果

接受 REAC 脑刺激治疗后,所有患者的焦虑和抑郁均显著减轻。这些结果通过医生检查、HAM-D 评分和 SCL-90R 总分得到证实。

结论

这些结果表明,REAC 脑刺激在管理精神疾病方面,特别是 GAD-MD 共病方面具有一定作用。REAC 治疗与药物治疗具有协同作用,似乎有助于减少药物的副作用。未来的研究应评估 REAC 治疗的长期效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2f4/3157488/970981fa633b/ndt-7-449f1.jpg

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