Key Laboratory of Traditional Chinese Medicine Resource and Compound Prescription of the Ministry of Education, Hubei University of Chinese Medicine, No. 1 West Huangjia Lake Road, Hongshan District, Hubei, Wuhan 430065, China.
Evid Based Complement Alternat Med. 2012;2012:945824. doi: 10.1155/2012/945824. Epub 2011 Aug 11.
In the recent years, a wide range of metabonomic technologies are widely used in the modern research of traditional chinese medicine (TCM). At present, the most prevailing methods for TCM research are mainly nuclear magnetic resonance (NMR), gas chromatography-mass spectrometry (GC-MS), and liquid chromatography-mass spectrometry (LC-MS). With these techniques, metabonomics will help to understand syndromes, efficacy and toxicity of TCM. However, every analytical technique has its advantages and drawbacks, and there exist some obstacles of its applications on TCM. So, we discuss metabonomics in TCM and analyze some problems of its applications to study TCM in recent years. We believe that with the further development of metabonomic analytical technology, especially multianalysed techniques, metabonomics will greatly promote TCM research and be beneficial to the modernization of TCM.
近年来，广泛的代谢组学技术被广泛应用于中药（TCM）的现代研究中。目前，TCM 研究中最流行的方法主要是核磁共振（NMR）、气相色谱-质谱联用（GC-MS）和液相色谱-质谱联用（LC-MS）。通过这些技术，代谢组学将有助于了解中药的证候、功效和毒性。然而，每种分析技术都有其优点和缺点，在中药应用上也存在一些障碍。因此，我们讨论了代谢组学在中药中的应用，并分析了近年来应用于中药研究的一些问题。我们相信，随着代谢组学分析技术的进一步发展，特别是多分析技术的发展，代谢组学将极大地促进中药的研究，有利于中药的现代化。
