Moss Rehabilitation Research Institute, Philadelphia, PA, USA.
J Cogn Neurosci. 2012 Jan;24(1):212-22. doi: 10.1162/jocn_a_00118. Epub 2011 Aug 23.
We explored the neural basis of reversible sentence comprehension in a large group of aphasic patients (n = 79). Voxel-based lesion symptom mapping revealed a significant association between damage in temporo-parietal cortex and impaired sentence comprehension. This association remained after we controlled for phonological working memory. We hypothesize that this region plays an important role in the thematic or what-where processing of sentences. In contrast, we detected weak or no association between reversible sentence comprehension and the ventrolateral pFC, which includes Broca's area, even for syntactically complex sentences. This casts doubt on theories that presuppose a critical role for this region in syntactic computations.
我们在一大群失语症患者（n = 79）中探索了可逆句子理解的神经基础。基于体素的病变症状映射显示，颞顶叶皮层的损伤与句子理解受损之间存在显著关联。在控制了语音工作记忆之后，这种关联仍然存在。我们假设这个区域在句子的主题或什么-哪里处理中发挥重要作用。相比之下，我们在可逆句子理解和包括布罗卡区的腹外侧额下回之间检测到微弱或没有关联，即使对于语法复杂的句子也是如此。这对假设该区域在句法计算中起关键作用的理论提出了质疑。
