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局部麻醉下第二只眼白内障手术中的疼痛:一项个体内研究。

Pain during second eye cataract surgery under topical anesthesia: an intraindividual study.

机构信息

Divisione Oculistica, Ospedale San Pietro-Fatebenefratelli, Via Cassia 600, 00189, Rome, Italy.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2011 Oct;249(10):1511-4. doi: 10.1007/s00417-011-1803-9. Epub 2011 Aug 24.

DOI:10.1007/s00417-011-1803-9
PMID:21863254
Abstract

BACKGROUND

Aim of the study was to investigate: 1) if second eye cataract surgery under topical anesthesia is more painful than surgery on the first eye, 2) if pain experienced during the procedure on the first eye may predict the pain of the second procedure, and 3) if patients' cooperation is different between the first and the second eye procedure.

METHODS

Seventy-three consecutive patients undergoing bilateral non-simultaneous cataract surgery were prospectively included in the study. Surgical technique was sutureless clear corneal phacoemulsification under topical anesthesia. Immediately after surgery every patient graded the pain experienced using a visual analogue scale (VAS) from 0 (no pain) to 10 (unbearable pain). At the end of each procedure the surgeon graded patients' cooperation using a 4-point scale.

RESULTS

Mean VAS score was 2.35 (SD 2.63) for the first eye and 2.89 (SD 2.93) for the second eye. Such a difference was not statistically significant (p = 0.1777, Wilcoxon test). The correlation between the VAS score of the first and that of the second procedure was statistically significant (r = 0.5514, p < 0.0001, Spearman rank correlation). Patients' cooperation was 2.64 (SD 0.63) during the first procedure and 2.52 (SD 0.79) during the second procedure; this difference was not statistically significant (p = 0.1769, Wilcoxon matched-pairs signed-ranks test).

CONCLUSIONS

After uneventful cataract surgery under topical anesthesia, pain experienced and cooperation did not differ between first and second eye procedures. A correlation was found between pain scores of the first and the second eye procedures.

摘要

背景

本研究旨在探讨:1)局部麻醉下第二只眼白内障手术是否比第一只眼手术更痛,2)第一只眼手术过程中的疼痛是否可预测第二只眼手术的疼痛,以及 3)患者在第一只眼和第二只眼手术中的配合是否不同。

方法

73 例连续接受双侧非同期白内障手术的患者前瞻性纳入本研究。手术技术为无缝线透明角膜超声乳化术,局部麻醉。术后即刻,每位患者使用视觉模拟评分(VAS)从 0(无痛)到 10(无法忍受的疼痛)对所经历的疼痛进行分级。在每只眼手术结束时,外科医生使用 4 分制对患者的配合进行分级。

结果

第一只眼的平均 VAS 评分为 2.35(SD 2.63),第二只眼为 2.89(SD 2.93)。这种差异无统计学意义(p=0.1777,Wilcoxon 检验)。第一只眼和第二只眼手术的 VAS 评分之间的相关性具有统计学意义(r=0.5514,p<0.0001,Spearman 等级相关)。第一只眼手术时患者的配合评分为 2.64(SD 0.63),第二只眼为 2.52(SD 0.79);这种差异无统计学意义(p=0.1769,Wilcoxon 配对符号秩检验)。

结论

在局部麻醉下顺利进行白内障手术后,第一只眼和第二只眼手术过程中的疼痛和配合无差异。第一只眼和第二只眼手术的疼痛评分之间存在相关性。

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本文引用的文献

1
Local anesthesia for cataract surgery.白内障手术的局部麻醉。
J Cataract Refract Surg. 2010 Jan;36(1):133-52. doi: 10.1016/j.jcrs.2009.10.025.
2
Topical anaesthesia alone versus topical anaesthesia with intracameral lidocaine for phacoemulsification.单纯表面麻醉与前房内注射利多卡因联合表面麻醉用于白内障超声乳化手术的比较
Cochrane Database Syst Rev. 2007 Jul 18(3):CD005276. doi: 10.1002/14651858.CD005276.pub2.
3
Patient perceptions of second eye clear corneal cataract surgery using assisted topical anaesthesia.患者对使用辅助表面麻醉的右眼透明角膜白内障手术的认知
接受即刻连续双侧白内障手术或单侧白内障手术患者的焦虑与疼痛分析。
Sci Rep. 2025 Feb 1;15(1):3971. doi: 10.1038/s41598-025-87359-z.
4
Pain perception enhancement in consecutive second-eye phacoemulsification cataract surgeries under topical anesthesia.表面麻醉下连续进行的第二眼超声乳化白内障手术中疼痛感知增强
Int J Ophthalmol. 2024 Aug 18;17(8):1510-1518. doi: 10.18240/ijo.2024.08.18. eCollection 2024.
5
Comparison of pain between bilateral ICL surgeries in patients with myopia.双眼 ICL 手术治疗近视患者的疼痛比较。
BMC Ophthalmol. 2024 Apr 16;24(1):175. doi: 10.1186/s12886-024-03450-5.
6
Comparison of Pain between First and Second Operated Eyelids after Upper Eyelid Blepharoplasty.双眼皮术后初次与再次手术的上眼睑疼痛比较。
Korean J Ophthalmol. 2023 Jun;37(3):201-206. doi: 10.3341/kjo.2023.0011. Epub 2023 Apr 17.
7
Can lubrication of the eyelid speculum reduce overall pain perception associated with cataract surgery by phacoemulsification performed under topical anesthesia?表面麻醉下超声乳化白内障摘除术中使用眼睑撑开器润滑能否减轻手术相关的总体疼痛?
Indian J Ophthalmol. 2022 May;70(5):1606-1611. doi: 10.4103/ijo.IJO_2963_21.
8
Sympathetic Nerve-Mediated Fellow Eye Pain During Sequential Cataract Surgery by Regulating Granulocyte Colony Stimulating Factor CSF3.交感神经通过调节粒细胞集落刺激因子CSF3介导白内障序贯手术期间的健眼疼痛
Front Cell Neurosci. 2022 Feb 24;16:841733. doi: 10.3389/fncel.2022.841733. eCollection 2022.
9
Do Consecutive Phacoemulsification Surgeries Under Topical Anesthesia Differ in Terms of Pain Perception and Cooperation?表面麻醉下连续进行的白内障超声乳化手术在疼痛感知和配合度方面是否存在差异?
Cureus. 2021 Nov 26;13(11):e19915. doi: 10.7759/cureus.19915. eCollection 2021 Nov.
10
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J Immunol Res. 2021 Aug 25;2021:7377685. doi: 10.1155/2021/7377685. eCollection 2021.
Eye (Lond). 2008 Apr;22(4):547-50. doi: 10.1038/sj.eye.6702711. Epub 2007 Feb 2.
4
Prospective randomized double-masked trial to evaluate perioperative pain profile in different stages of simultaneous bilateral LASIK.评估同期双侧准分子激光原位角膜磨镶术(LASIK)不同阶段围手术期疼痛情况的前瞻性随机双盲试验。
Cornea. 2006 Sep;25(8):919-22. doi: 10.1097/01.ico.0000226363.19054.2a.
5
Lidocaine 2% gel versus lidocaine 4% unpreserved drops for topical anesthesia in cataract surgery: a randomized controlled trial.2%利多卡因凝胶与4%无防腐剂利多卡因滴眼液用于白内障手术局部麻醉的随机对照试验。
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