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2
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6
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Cohort profile: The Guangzhou Biobank Cohort Study, a Guangzhou-Hong Kong-Birmingham collaboration.队列简介：广州生物样本库队列研究，一项广州-香港-伯明翰的合作项目。
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自我报告的总睡眠时间过长与代谢综合征有关：广州生物银行队列研究。

Self-reported long total sleep duration is associated with metabolic syndrome: the Guangzhou Biobank Cohort Study.

机构信息

Birmingham and Black Country National Institute for Health Research Collaborations for Leadership in Applied Health Research and Care, University of Birmingham, Birmingham, UK.

出版信息

Diabetes Care. 2011 Oct;34(10):2317-9. doi: 10.2337/dc11-0647. Epub 2011 Aug 26.

DOI:10.2337/dc11-0647
PMID:21873559
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3177714/
Abstract

OBJECTIVE

To examine the association between total sleep duration and the prevalence of metabolic syndrome (MetSyn) in older Chinese.

RESEARCH DESIGN AND METHODS

Cross-sectional analysis of baseline data from the Guangzhou Biobank Cohort Study (GBCS) was performed. Participants (n = 29,333) were aged ≥50 years. Risk of MetSyn and its components were identified for self-reported total sleep duration.

RESULTS

Participants reporting long (≥9 h) and short (<6 h) total sleep duration had increased odds ratio (OR) of 1.18 (95% CI 1.07-1.30) and 1.14 (1.05-1.24) for the presence of MetSyn, respectively. The relationship remained in long sleepers (OR 1.21 [1.10-1.34]) but diminished in short sleepers (0.97 [0.88-1.06]) after full adjustment.

CONCLUSIONS

Long sleep duration was associated with greater risk of MetSyn in older Chinese. Confirmation through longitudinal studies is needed. The mechanisms mediating the link between long sleep duration and MetSyn require further investigation.

摘要

目的

研究中国老年人总睡眠时间与代谢综合征（MetSyn）患病率之间的关系。

研究设计和方法

对广州生物库队列研究（GBCS）的基线数据进行横断面分析。参与者年龄≥50 岁。根据自我报告的总睡眠时间，确定 MetSyn 及其各组成部分的风险。

结果

报告总睡眠时间较长（≥9 小时）和较短（<6 小时）的参与者发生 MetSyn 的比值比（OR）分别为 1.18（95%CI，1.07-1.30）和 1.14（1.05-1.24）。在充分调整后，长睡眠者（OR 1.21[1.10-1.34]）的这种关系仍然存在，但短睡眠者（0.97[0.88-1.06]）的关系减弱。

结论

在中国老年人中，长睡眠时间与 MetSyn 的风险增加有关。需要通过纵向研究加以证实。介导长睡眠时间与 MetSyn 之间关联的机制需要进一步研究。