Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands.
Eur J Nutr. 2012 Aug;51(5):583-91. doi: 10.1007/s00394-011-0242-z. Epub 2011 Aug 30.
We aimed to examine the association between intake of different subgroups of dairy products and blood pressure and incident hypertension 10 years later, adjusting for confounding factors.
We studied 1,750 British men and women from the 1946 British birth cohort from 1989 to 1999 (age 43 and 53 years, respectively). Diet was assessed by 5-day food diaries using photographs in the estimation of portion size. Systolic (sbp) and diastolic (dbp) blood pressure and prevalent hypertension were assessed at age 43 and 53 years. Linear regression and logistic regression were used to examine 10-year blood pressure levels and incident hypertension by baseline dairy intake.
There was a weak non-significant trend of a protective effect of total dairy intake on blood pressure and incident hypertension, but no evidence for a dose-response relationship (OR for incident hypertension: 0.88 (95% CI 0.68;1.14) 2nd vs. 1st tertile and 0.93 (95% CI 0.72;1.18) 3rd vs. 1st tertile). Higher intake of low-fat and fermented dairy was linked to a higher sbp but in a nonlinear manner. Adjustment for other dietary factors, health behaviours and BMI attenuated these associations.
Total dairy intake and specific dairy subgroups were not associated with blood pressure and incident hypertension among a representative sample of British adults after adjustment for confounding factors.
我们旨在研究不同亚组乳制品的摄入量与血压之间的关联，并在调整混杂因素后评估其与 10 年后高血压发病的关系。
我们研究了来自 1946 年英国出生队列的 1750 名英国男性和女性，他们在 1989 年至 1999 年期间（分别为 43 岁和 53 岁）进行了 5 天的饮食日记，通过照片来估计食物份量。在 43 岁和 53 岁时评估收缩压（sbp）和舒张压（dbp）以及现患高血压情况。线性回归和逻辑回归用于根据基线乳制品摄入量来评估 10 年血压水平和新发高血压情况。
总乳制品摄入量与血压和新发高血压呈弱非显著的保护趋势，但没有剂量反应关系的证据（新发高血压的比值比：0.88（95%可信区间 0.68；1.14）第 2 组与第 1 组，0.93（95%可信区间 0.72；1.18）第 3 组与第 1 组）。较高的低脂和发酵乳制品摄入量与更高的 sbp 有关，但呈非线性关系。调整其他饮食因素、健康行为和 BMI 后，这些关联减弱。
在调整混杂因素后，在具有代表性的英国成年人样本中，总乳制品摄入量和特定乳制品亚组与血压和新发高血压之间没有关联。
