Division of Epidemiology and Community Health, University of Minnesota School of Public Health, 1300 South 2nd Street, Suite 300, Minneapolis, MN 55454, USA.
Nutrients. 2013 May 21;5(5):1719-33. doi: 10.3390/nu5051719.
Dietary intake among other lifestyle factors influence blood pressure. We examined the associations of an "a priori" diet score with incident high normal blood pressure (HNBP; systolic blood pressure (SBP) 120-139 mmHg, or diastolic blood pressure (DBP) 80-89 mmHg and no antihypertensive medications) and hypertension (SBP ≥ 140 mmHg, DBP ≥ 90 mmHg, or taking antihypertensive medication). We used proportional hazards regression to evaluate this score in quintiles (Q) and each food group making up the score relative to incident HNBP or hypertension over nine years in the Atherosclerosis Risk of Communities (ARIC) study of 9913 African-American and Caucasian adults aged 45-64 years and free of HNBP or hypertension at baseline. Incidence of HNBP varied from 42.5% in white women to 44.1% in black women; and incident hypertension from 26.1% in white women to 40.8% in black women. Adjusting for demographics and CVD risk factors, the "a priori" food score was inversely associated with incident hypertension; but not HNBP. Compared to Q1, the relative hazards of hypertension for the food score Q2-Q5 were 0.97 (0.87-1.09), 0.91 (0.81-1.02), 0.91 (0.80-1.03), and 0.86 (0.75-0.98); p(trend) = 0.01. This inverse relation was largely attributable to greater intake of dairy products and nuts, and less meat. These findings support the 2010 Dietary Guidelines to consume more dairy products and nuts, but suggest a reduction in meat intake.
饮食摄入和其他生活方式因素会影响血压。我们研究了一种“先验”饮食评分与新发正常高值血压(HNBP;收缩压(SBP)120-139mmHg,或舒张压(DBP)80-89mmHg,且未服用降压药物)和高血压(SBP≥140mmHg,DBP≥90mmHg,或服用降压药物)的相关性。我们使用比例风险回归分析评估了五分位数(Q)中的该评分,以及构成评分的每个食物组与 9 年内发生的 HNBP 或高血压之间的相关性。在 ARIC 研究中,9913 名年龄在 45-64 岁、基线时无 HNBP 或高血压的非裔美国人和白种成年人中,HNBP 的发生率从白人女性的 42.5%到黑人女性的 44.1%不等;高血压的发生率从白人女性的 26.1%到黑人女性的 40.8%不等。调整人口统计学和心血管疾病危险因素后,“先验”食物评分与新发高血压呈负相关;但与 HNBP 无关。与 Q1 相比,食物评分 Q2-Q5 发生高血压的相对危险度分别为 0.97(0.87-1.09)、0.91(0.81-1.02)、0.91(0.80-1.03)和 0.86(0.75-0.98);p(趋势)=0.01。这种反比关系主要归因于摄入更多的乳制品和坚果,以及更少的肉类。这些发现支持 2010 年饮食指南建议摄入更多的乳制品和坚果,但建议减少肉类摄入。