Ismail S O, Ahmed H J, Jama M A, Omer K, Omer F M, Brundin M, Olofsson M B, Grillner L, Bygdeman S
Department of Pathology and Morphology, Karolinska Hospital, Stockholm, Sweden.
Genitourin Med. 1990 Apr;66(2):70-5. doi: 10.1136/sti.66.2.70.
A total of 767 sera were collected from 187 men, 200 women and 380 children in a Somali village, Jambaluul. All sera were tested for syphilis serological markers by Venereal Diseases Research Laboratory (VDRL) and Treponema pallidum Haemagglutination Assay (TPHA). Sera positive for both or either of these tests were further analysed for the presence of specific IgM antibodies by Solid Phase Haemadsorption Assay (SPHA). A high and almost equal prevalence of TPHA positivity was found in men and women; 24% and 22.5%, respectively, and IgM antibodies were found in 3% and 4%, respectively. TPHA positivity significantly increased with age. Thus more than half of the villagers at the age of 45 years or more were TPHA positive. One percent of the children were TPHA positive. From all adults aged 15 years and above urogenital specimens were also taken for Chlamydia trachomatis antigen detection with an enzyme-amplified immunoassay (IDEIA) and Neisseria gonorrhoeae culture. Chlamydial genital infection was found in 6% of the men and 18% of the women. All gonococcal cultures were negative.
在索马里一个名为詹巴卢尔的村庄，共采集了767份血清样本，其中男性187人、女性200人、儿童380人。所有血清样本均通过性病研究实验室（VDRL）试验和梅毒螺旋体血凝试验（TPHA）检测梅毒血清学标志物。对这两项检测中任一项或两项均呈阳性的血清样本，进一步采用固相血细胞吸附试验（SPHA）分析特异性IgM抗体的存在情况。结果发现，男性和女性的TPHA阳性率较高且几乎相等，分别为24%和22.5%，而IgM抗体阳性率分别为3%和4%。TPHA阳性率随年龄显著增加。因此，45岁及以上的村民中，超过一半的人TPHA呈阳性。儿童中TPHA阳性率为1%。对所有15岁及以上的成年人，还采集了泌尿生殖系统标本，采用酶放大免疫测定法（IDEIA）检测沙眼衣原体抗原，并进行淋病奈瑟菌培养。结果发现，男性衣原体生殖器感染率为6%，女性为18%。所有淋病奈瑟菌培养均为阴性。
